Evidence map›Paper›PMID 18064487›Full record

ArticlePflugers Archiv : European journal of physiology2008

An historical perspective on cell mechanics.

Andrew E Pelling, Michael A Horton

Abstract readHistorical Article
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. The Elephant in the Cell: Nuclear Mechanics and Mechanobiology.Journal of biomechanical engineering · 2022
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Application of Micropipette Aspiration in Molecular Mechanics of Single Cells.Journal of nanotechnology in engineering and medicine · 2014
    Review
  7. Review
  8. Article
  9. Polymer physics of the cytoskeleton.Current opinion in solid state & materials science · 2011
    Article
  10. Article
  11. The mechanical cell.Current biology : CB · 2009
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew E PellingThe London Centre for Nanotechnology, Centre for Nanomedicine, University College London, 17-19 Gordon Street, London WC1H 0AH, UK. a.pelling@ucl.ac.uk
Michael A Horton

Funding

Wellcome Trust
6 · The paper itself

Abstract

The physical properties of the protoplasm have long been of interest, and today, several intricate methods, including atomic force microscopy, have been employed in studies of cellular mechanics. However, many current concepts and experimental approaches actually have their beginnings over 300 years ago. Unfortunately, these pioneering studies have been all but forgotten. In this paper, we have reviewed some of the early literature on cellular mechanics to place modern work within an historical framework. It is clear that with current nanoscience approaches, modern experiments employing cell indentation, manipulation, particle rheology and micro- or nano-needle poking are now quantifying mechanical properties which were only qualitatively described 100 years ago. Aside from the variety of approaches our predecessors have employed to understand cellular mechanics, we feel an understanding of the past will help to propel nanoscience into the future. As nanophysiology and nanomedicine are developing, we as a community should take time to consider the early roots of these fields.

Indexed as

Cell Physiological PhenomenaAnimalsBiomechanical PhenomenaCell BiologyCellsCytoplasmHistory, 18th CenturyHistory, 19th CenturyHistory, 20th CenturyHistory, 21st CenturyHumansMicroscopyMicroscopy, Atomic Force

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.