ArticlePlant molecular biology2008
Differential requirement for the function of SRD2, an snRNA transcription activator, in various stages of plant development.
Article in Plant molecular biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Pre-mRNA Splicing Functions in Plant Sexual Reproduction Development.Plants (Basel, Switzerland) · 2025Review
- Chemically-induced cellular stress signals are transmitted to alternative splicing via UsnRNA levels to alter gene expression in Arabidopsis thaliana.Plant molecular biology · 2025Article
- Transcriptional regulation of cell proliferation competence-associated Arabidopsis genes,Plant biotechnology (Tokyo, Japan) · 2022Article
- Functional and evolutionary analysis of the Arabidopsis 4R-MYB protein SNAPc4 as part of the SNAP complex.Plant physiology · 2021Article
- Alternative splicing of DSP1 enhances snRNA accumulation by promoting transcription termination and recycle of the processing complex.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- DSP1 and DSP4 Act Synergistically in Small Nuclear RNA 3' End Maturation and Pollen Growth.Plant physiology · 2019Article
- Arabidopsis Group IIId ERF proteins positively regulate primary cell wall-type CESA genes.Journal of plant research · 2019Article
- Plant snRNP Biogenesis: A Perspective from the Nucleolus and Cajal Bodies.Frontiers in plant science · 2017Review
- Transcriptional regulation of snRNAs and its significance for plant development.Journal of plant research · 2017Review
- Cell dedifferentiation and organogenesis in vitro require more snRNA than does seedling development in Arabidopsis thaliana.Journal of plant research · 2015Article
- Regulation of RNA metabolism is important for in vitro dedifferentiation of plant cells.Journal of plant research · 2015Article
- Arabidopsis root initiation defective1, a DEAH-box RNA helicase involved in pre-mRNA splicing, is essential for plant development.The Plant cell · 2013Article
- Twist of fate: RID1, a DEAH-box RNA helicase involved in pre-mRNA splicing, is crucial for development.The Plant cell · 2013Article
- How do 'housekeeping' genes control organogenesis?--Unexpected new findings on the role of housekeeping genes in cell and organ differentiation.Journal of plant research · 2013Review
- VND-INTERACTING2, a NAC domain transcription factor, negatively regulates xylem vessel formation in Arabidopsis.The Plant cell · 2010Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small nuclear RNA (snRNA) is a class of eukaryotic noncoding RNAs, which have essential roles in pre-mRNA splicing and rRNA processing. As these functions are fundamental to cell activities, the regulation of snRNA transcription should be a vital issue for all eukaryotes. Here we address developmental control of snRNA transcription and its significance through the analysis of the SRD2 gene of Arabidopsis (Arabidopsis thaliana), which encodes an activator of snRNA transcription. In young seedlings, a high level of SRD2 expression was observed in shoot and root apical meristems, leaf primordia, and root stele tissues, where a large amount of snRNA accumulated. In mature plants, SRD2 was highly expressed in developing leaves and flowers as well as apical meristems. Mutations in the SRD2 gene interfered with many, but not all, aspects of development in the regions that showed strong expression of SRD2. Of note, establishment of the fully active state of apical meristems in the seedling stage was very sensitive to the srd2-1 mutation, while maintenance of the established meristems was substantially insensitive. These results demonstrated differential requirement for the SRD2 function in various stages of plant development.
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