ReviewMicrobiology and molecular biology reviews : MMBR2007
Function, structure, and evolution of the RubisCO-like proteins and their RubisCO homologs.
Review in Microbiology and molecular biology reviews : MMBR, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
150 citing papers in PubMed, 389 citations in OpenAlex.
- Harnessing natural variation for photosynthetic improvement in next-generation crop breeding.Journal of integrative plant biology · 2026Review
- Moss Cover Redirects Soil Organic Carbon from Active Turnover to Mineral-Associated Stabilization in Subalpine Forests.Plants (Basel, Switzerland) · 2026Article
- Diversity-driven biochemical survey reveals widespread dimerization throughout the rubisco superfamily.Nature communications · 2026Article
- A synthetic expression system for orthogonal gene expression in Nicotiana benthamiana.Plant molecular biology · 2026Article
- Host species-specific gene expression by a widespread and flexible chemosynthetic symbiont.The ISME journal · 2026Article
- Genomic and metagenomic survey of microbial carbonic anhydrase genes reveals novel clades, high diversity, and biome specificity.ISME communications · 2026Article
- On the emergence of metabolism: the evolution of proteins that powered life.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Restoring cytonuclear harmony: Distinct strategies in Arabidopsis auto- and allopolyploids.The Plant journal : for cell and molecular biology · 2025Article
- High-resolution structure of the heat-stable form-IAq RuBisCO from the thermophilic purple sulfur bacterium Thermochromatium tepidum.Scientific reports · 2025Article
- Understanding carboxysomes to enhance carbon fixation in crops.Biochemical Society transactions · 2025Review
- Review
- Differential diversity and structure of autotrophs in agricultural soils of Qinghai Province.Microbiology spectrum · 2025Article
- Evolutionary Dynamics of RuBisCO: Emergence of the Small Subunit and its Impact Through Time.Molecular biology and evolution · 2025Article
- Aspergillus-derived β-glucan nanoparticles: a dual strategy forFrontiers in plant science · 2025Article
- Spatiotemporal and temperature-dependent disconnect between ammonia oxidation and dark DIC fixation in deep oligotrophic Lake Constance.ISME communications · 2025Article
- Cyanobacteria from marine oxygen-deficient zones encode both form I and form II Rubiscos.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Engineering Rubisco to enhance COSynthetic and systems biotechnology · 2024Review
- The Complete Genome of a Novel Typical SpeciesMicroorganisms · 2024Article
- Multi-environment ecogenomics analysis of the cosmopolitan phylum Gemmatimonadota.Microbiology spectrum · 2023Article
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
About 30 years have now passed since it was discovered that microbes synthesize RubisCO molecules that differ from the typical plant paradigm. RubisCOs of forms I, II, and III catalyze CO(2) fixation reactions, albeit for potentially different physiological purposes, while the RubisCO-like protein (RLP) (form IV RubisCO) has evolved, thus far at least, to catalyze reactions that are important for sulfur metabolism. RubisCO is the major global CO(2) fixation catalyst, and RLP is a somewhat related protein, exemplified by the fact that some of the latter proteins, along with RubisCO, catalyze similar enolization reactions as a part of their respective catalytic mechanisms. RLP in some organisms catalyzes a key reaction of a methionine salvage pathway, while in green sulfur bacteria, RLP plays a role in oxidative thiosulfate metabolism. In many organisms, the function of RLP is unknown. Indeed, there now appear to be at least six different clades of RLP molecules found in nature. Consideration of the many RubisCO (forms I, II, and III) and RLP (form IV) sequences in the database has subsequently led to a coherent picture of how these proteins may have evolved, with a form III RubisCO arising from the Methanomicrobia as the most likely ultimate source of all RubisCO and RLP lineages. In addition, structure-function analyses of RLP and RubisCO have provided information as to how the active sites of these proteins have evolved for their specific functions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.