Evidence map›Paper›PMID 18061385›Full record

ReviewExperimental gerontology2008

Drosophila aging 2006/2007.

Paul Shaw, Karen Ocorr, Rolf Bodmer, Sean Oldham

Abstract readReview
In one paragraph

Review in Experimental gerontology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Automated Tracking of Drosophila Specimens.Sensors (Basel, Switzerland) · 2015
    Article
  5. Article
  6. Studying aging in Drosophila.Methods (San Diego, Calif.) · 2014
    Review
  7. Review
  8. Article
  9. Aging in the glomerulus.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012
    Review
  10. Article
  11. Article
  12. Podocytes and glomerular function with aging.Seminars in nephrology · 2009
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paul ShawDepartment of Anatomy and Neurobiology, Washington University, School of Medicine, St Louis, MO 63110, USA. shawp@pcg.wustl.edu
Karen Ocorr
Rolf Bodmer
Sean Oldham
Washington University in St. Louis · US

Funding

Control of fat accumulation in relation to cardiac function in DrosophilaR01HL084949 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI BODMER, ROLF · 2005 to 2008
$1.8M
NHLBI NIH HHS R01 HL084949
6 · The paper itself

Abstract

Research on aging in Drosophila continues to provide new insights into this complex process. Drosophila is highly amenable to study aging because of its short generation time, comprehensive resources for genetic manipulation, and functionally conserved physiology. Importantly, many of these physiological processes such as heart function, sleep, and metabolism functionally senescence in older flies. As the evolutionarily conserved insulin and TOR pathways are critical regulators of aging, the influence of insulin and TOR signaling on these processes is an important area for future research. An important emerging theme is determining the age-dependent alterations that occur at the organ level and how this functional senescence is regulated by different tissues.

Indexed as

AgingAnimalsDrosophilaDrosophila ProteinsFemaleLongevityMaleModels, AnimalOxidative StressReproductionSleepDrosophila Proteins

Identifiers

PMID18061385
PMCPMC2223272
OpenAlexW2030268256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.