Evidence map›Paper›PMID 18061103›Full record

ReviewGastrointestinal endoscopy clinics of North America2008

Esophageal dysmotility in patients who have eosinophilic esophagitis.

Samuel Nurko, Rachel Rosen

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Gastrointestinal endoscopy clinics of North America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06665971 (Effect of Dupilumab on Esophageal Peristaltic Function in Participants with Eosinophilic Esophagitis), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06665971 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Dupilumab on Esophageal Peristaltic Function in Participants with Eosinophilic Esophagitis

TypeinterventionalSponsorUniversity of California, San DiegoRan2024 to 2026Enrolled30ConditionsEosinophilic Esophagitis (EoE)ArmsDupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Review
  4. Future perspectives in esophageal manometry.World journal of gastrointestinal surgery · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Dysmotility in Eosinophilic Esophagitis.Frontiers in pediatrics · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Acute intramucosal dissection in eosinophilic esophagitis.Clinical journal of gastroenterology · 2019
    Article
  14. UEG Week 2019 Poster Presentations.United European gastroenterology journal · 2019
    Article
  15. Article
  16. Review
  17. Eosinophilic esophagitis: New insights in pathogenesis and therapy.World journal of gastrointestinal pharmacology and therapeutics · 2016
    Review
  18. Association of achalasia and eosinophilic esophagitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2013
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Samuel NurkoCenter for Motility and Functional Gastrointestinal Disorders, Children's Hospital Boston, Hunnewell - Ground, 300 Longwood Avenue, Boston, MA 02115, USA. samuel.nurko@childrens.harvard.edu <samuel.nurko@childrens.harvard.edu>
Rachel Rosen
Boston Children's Hospital · US

Funding

Impact of non-acid reflux on respiratory diseases in childrenK23DK073713 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI ROSEN, RACHEL L · 2007 to 2011
$645k
NIDDK NIH HHS K23 DK073713
6 · The paper itself

Abstract

The understanding of esophageal motility alterations in patients who have eosinophilic esophagitis (EE) is in its infancy despite the common presenting complaint of dysphagia. A diversity of motility disorders has been reported in patients who have EE including achalasia, diffuse esophageal spasm, nutcracker esophagus, and nonspecific motility alterations including high-amplitude esophageal body contractions, tertiary contractions, abnormalities in lower esophageal sphincter pressure, and other peristaltic problems. Some evidence suggests that treatment of EE will improve motility. Technological advances such as high-resolution manometry and combined manometry with impedance may provide new insight into more subtle motility abnormalities.

Indexed as

Deglutition DisordersEosinophiliaEosinophilsEsophageal AchalasiaEsophageal Motility DisordersEsophagitisEsophagusHumansManometryMast Cells

Identifiers

PMID18061103
PMCPMC3001401
OpenAlexW2034397355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.