ReviewHistochemistry and cell biology2008
Assembly, organization, and function of the COPII coat.
Review in Histochemistry and cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
65 citing papers in PubMed.
- Vacuolar (HGenes · 2025Article
- Article
- Generation of nanoscopic membrane curvature for membrane trafficking.Nature reviews. Molecular cell biology · 2023Review
- Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage.Nature communications · 2022Article
- A monoallelic SEC23A variant E599K associated with cranio-lenticulo-sutural dysplasia.American journal of medical genetics. Part A · 2022Article
- The Golgi Apparatus and its Next-Door Neighbors.Frontiers in cell and developmental biology · 2022Review
- Combinatorial multivalent interactions drive cooperative assembly of the COPII coat.The Journal of cell biology · 2020Article
- Autophagic Proteome in TwoMicroorganisms · 2020Article
- Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2.Nature chemical biology · 2020Article
- Gene expression profiles that shape high and low oil content sesames.BMC genetics · 2019Article
- A genome-wide analysis of coatomer protein (COP) subunits of apicomplexan parasites and their evolutionary relationships.BMC genomics · 2019Article
- COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways.Nucleic acids research · 2018Article
- Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression.EBioMedicine · 2018Article
- Review
- Endoplasmic reticulum-associated degradation and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei.Molecular biology of the cell · 2018Article
- In focus in HCB.Histochemistry and cell biology · 2018Article
- COPII-dependent ER export in animal cells: adaptation and control for diverse cargo.Histochemistry and cell biology · 2018Review
- CREB3L1-mediated functional and structural adaptation of the secretory pathway in hormone-stimulated thyroid cells.Journal of cell science · 2017Article
- Identification of Cysteine Ubiquitylation Sites on the Sec23A Protein of the COPII Complex Required for Vesicle Formation from the ER.The open biochemistry journal · 2017Article
- Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A full mechanistic understanding of how secretory cargo proteins are exported from the endoplasmic reticulum for passage through the early secretory pathway is essential for us to comprehend how cells are organized, maintain compartment identity, as well as how they selectively secrete proteins and other macromolecules to the extracellular space. This process depends on the function of a multi-subunit complex, the COPII coat. Here we describe progress towards a full mechanistic understanding of COPII coat function, including the latest findings in this area. Much of our understanding of how COPII functions and is regulated comes from studies of yeast genetics, biochemical reconstitution and single cell microscopy. New developments arising from clinical cases and model organism biology and genetics enable us to gain far greater insight in to the role of membrane traffic in the context of a whole organism as well as during embryogenesis and development. A significant outcome of such a full understanding is to reveal how the machinery and processes of membrane trafficking through the early secretory pathway fail in disease states.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.