ArticleMolecular biology reports2009
Identification and characterization of cyclin X which activates transcriptional activities of c-Myc.
Article in Molecular biology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Cytoplasmic Localization Isoform of Cyclin Y Enhanced the Metastatic Ability of Lung CancerFrontiers in cell and developmental biology · 2021Article
- Atypical cyclins: the extended family portrait.Cellular and molecular life sciences : CMLS · 2020Review
- Pharmacogenetic biomarkers of response in Crohn's disease.The pharmacogenomics journal · 2018Review
- Article
- [The function and molecular mechnism of cyclin Y protein].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2013Review
- Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.Molecular and cellular biology · 2012Article
- CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaques.Journal of medical primatology · 2012Article
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclins are eukaryotic proteins that play an active role in controlling cell division cycles and regulate cyclin dependent kinases (CDKs). In this study, we identified and characterized a new member of the human cyclin family. Its cDNA sequence contains an open reading frame of 864 bp, encoding a protein of 287 amino acids. This putative cyclin, designated cyclin X, contains a typical cyclin box. Cyclin X shows the highest sequence similarity in cyclin box to cyclin B3 and the similarity between these two proteins also extends to the whole molecule. The expression pattern of cyclin X showed that it was highly expressed in testis. Cyclin X protein was located in nucleus of the H1299 cells and Overexpression of cyclin X activated the transcriptional activities of c-Myc. These results indicate that cyclin X is a novel member of the human cyclin family and positive regulator of c-Myc-mediated gene transcription.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.