ArticleThe Journal of the Canadian Chiropractic Association2007
Ankylosing spondylitis: recent breakthroughs in diagnosis and treatment.
Article in The Journal of the Canadian Chiropractic Association, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line.Inflammopharmacology · 2018Trial
- Rehabilitation modalities in ankylosing spondylitis: orthopaedic perspectives on function, bone health, and surgical safety.Journal of orthopaedics · 2026Review
- Article
- Heart Rate Variability in Patients of Ankylosing Spondylitis: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- Oral manifestations associated with inflammatory bowel disease and early endoscopic findings in patients with spondyloarthritis.BMC oral health · 2022Article
- Diagnosis of Ankylosing Spondylitis: Do not let the spine bites the eye.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2021Article
- Comparison of the Effects of Secukinumab and Adalimumab Biosimilar on Radiographic Progression in Patients with Ankylosing Spondylitis: Design of a Randomized, Phase IIIb Study (SURPASS).Clinical drug investigation · 2020Article
- Real-World Patient Experience on the Path to Diagnosis of Ankylosing Spondylitis.Rheumatology and therapy · 2019Article
- Advances in nanomedicine for the treatment of ankylosing spondylitis.International journal of nanomedicine · 2019Review
- Tumor Necrosis Factor Inhibitor Discontinuation in Patients with Ankylosing Spondylitis: An Observational Study From the US-Based Corrona Registry.Rheumatology and therapy · 2018Article
- Ankylosing spondylitis causes high burden to patients and the healthcare system: results from a German claims database analysis.Rheumatology international · 2018Article
- Classification Terminology and Definitions in Reporting of MRI in Axial Spondyloarthritis.Journal of the Belgian Society of Radiology · 2017Article
- Analysis of the Literature on Cervical Spine Fractures in Ankylosing Spinal Disorders.Global spine journal · 2017Review
- High Prevalence of Undiagnosed Axial Spondyloarthritis in Patients with Chronic Low Back Pain Consulting Non-Rheumatologist Specialists in Belgium: SUSPECT Study.Rheumatology and therapy · 2017Article
- Ankylosing spondylitis: A state of the art factual backbone.World journal of radiology · 2015Review
- Use of spinal manipulation in a rheumatoid patient presenting with acute thoracic pain: a case report.The Journal of the Canadian Chiropractic Association · 2015Article
- Red blood cell distribution width: a potential maker estimating disease activity of ankylosing spondylitis.International journal of clinical and experimental medicine · 2014Article
- The patient experience with fatigue and content validity of a measure to assess fatigue severity: qualitative research in patients with ankylosing spondylitis (AS).Health and quality of life outcomes · 2013Article
- Screening and evaluating the mimic peptides as a useful serum biomarker of ankylosing spondylitis using a phage display technique.Rheumatology international · 2011Article
- From multidisciplinary to Interdisciplinary--it's all about patient outcomes.The Journal of the Canadian Chiropractic Association · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ankylosing spondylitis (AS) is generally easy to diagnose when the characteristic findings of the "bamboo" spine and fused sacroiliac joints are present on radiographs. Unfortunately, these changes are usually seen late in the disease after tremendous suffering has been incurred by the patient. Diagnostic delay averages seven to ten years. Historically, once the diagnosis was made, the treatment options were often inadequate or poorly tolerated in many individuals. This condition most often starts in early adulthood when people are typically in the earlier stages of their careers, resulting in diminished workforce participation and decreased quality of life. If an individual has a family physician, this might be the first encounter with a healthcare provider. Quite often, the initial practitioner is sought at a public walk-in clinic or chiropractic office. In recent years, there have been two major developments in the management of AS that make earlier diagnosis possible and offer the hope of alleviating pain and preventing structural changes that result in loss of function. These developments include the use of magnetic resonance imaging (MRI) to visualize the inflammatory changes in the sacroiliac joint and the axial spine, and the demonstration that tumor necrosis factor (TNF) blocking agents are highly efficacious in reducing spinal inflammation and possibly in slowing radiographic progression. This review outlines diagnostic strategies that can help identify AS in its earlier stages. Special attention is focused on treatment advances, including the use of anti-TNF agents, and how these medications have been incorporated into clinical recommendations for daily use.
Indexed as
Identifiers
18060011PMC2077878What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.