ArticleEMBO reports2007
Towards completion of the Earth's proteome.
Article in EMBO reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Prediction and validation of the unexplored RNA-binding protein atlas of the human proteome.Proteins · 2014Article
- A novel approach for protein subcellular location prediction using amino acid exposure.BMC bioinformatics · 2013Article
- Functional and genomic analyses of alpha-solenoid proteins.PloS one · 2013Article
- Preimplantation development regulatory pathway construction through a text-mining approach.BMC genomics · 2011Article
- Bioinformatics and genomic analysis of transposable elements in eukaryotic genomes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2011Article
- Génie: literature-based gene prioritization at multi genomic scale.Nucleic acids research · 2011Article
- Validation of coevolving residue algorithms via pipeline sensitivity analysis: ELSC and OMES and ZNMI, oh my!PloS one · 2010Article
- Quantitative global studies of reactomes and metabolomes using a vectorial representation of reactions and chemical compounds.BMC systems biology · 2010Article
- Linking genes to diseases: it's all in the data.Genome medicine · 2009Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New protein sequences are deposited in databases at an accelerating pace; however, many of these are homologous to known proteins and could be considered redundant. If all historical releases of the protein database are analysed using the original sequence-clustering procedure described here, the fraction of newly sequenced proteins that are redundant is increasing. We interpret this as an indication that the sequencing of the Earth's proteome--the complete set of proteins on Earth--is approaching completion. We estimate the approximate size of the Earth's proteome to be 5 million sequences, most of which will be identified during the next 5 years. As the Earth's proteome nears completion, cluster analysis of the protein database will become essential to identify under-explored taxa to which future sequencing efforts should be directed and to focus research on protein families without experimental characterization.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.