ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2008
Defining the role of surgery for primary gastrointestinal tract melanoma.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed, 151 citations in OpenAlex.
- The Development and Validation of a Nomogram for Predicting Cancer-Specific Survival and a Risk Stratification System for Patients with Primary Gastrointestinal Melanoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Trial
- Case Report: S-100 negative primary esophageal malignant melanoma: surgical challenges and phenotypic evolution.Frontiers in oncology · 2026Article
- Primary Jejunal Melanoma Presenting With Intussusception in a Patient With Chronic Iron Deficiency Anemia.ACG case reports journal · 2025Article
- Primary malignant melanoma of the small bowel: A case report.Radiology case reports · 2024Article
- Mucosal Melanoma: Epidemiology, Clinical Features, and Treatment.Current oncology reports · 2023Review
- Malignant primary melanoma of the colon: a case report.Journal of surgical case reports · 2023Article
- Incidence and survival of patients with primary gastrointestinal melanoma: a population-based study.International journal of colorectal disease · 2023Article
- A CT-Based Radiomics Nomogram Model for Differentiating Primary Malignant Melanoma of the Esophagus from Esophageal Squamous Cell Carcinoma.BioMed research international · 2023Article
- The different faces of metastatic melanoma in the gastrointestinal tract.Insights into imaging · 2022Review
- Primary colonic melanoma: a rare entity.World journal of surgical oncology · 2022Article
- Primary malignant melanoma of the esophagus: differentiation from esophageal squamous cell carcinoma and leiomyoma using dynamic contrast-enhanced CT findings.Abdominal radiology (New York) · 2022Article
- A case report of primary gastroesophageal melanoma: Presentation, diagnosis, and surgical approach.Annals of medicine and surgery (2012) · 2022Article
- Metastatic primary gastric melanoma: a rare clinical presentation and a review of literature.BMJ case reports · 2022Article
- Primary malignant melanoma of the esophagus.Clinical case reports · 2022Article
- Clinical characteristics and treatment outcomes of primary malignant melanoma of esophagus: a single center experience.BMC gastroenterology · 2022Article
- Primary malignant melanoma in gastroesophageal junction with 36 months' recurrence-free: a case report.AME case reports · 2022Article
- Clinicopathological Features, Staging Classification, and Clinical Outcomes of Esophageal Melanoma: Evaluation of a Pooled Case Series.Frontiers in oncology · 2022Article
- Primary gastric melanoma presenting with recurrent upper gastrointestinal bleeding.Annals of the Royal College of Surgeons of England · 2021Article
- Presentation, Management, and Prognosis of Primary Gastrointestinal Melanoma: A Population-Based Study.The Journal of surgical research · 2021Article
- A secondary jejunal malignant melanoma from nasal mucosal melanoma: Case report.SAGE open medical case reports · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of the study was to determine the outcomes for primary gastrointestinal melanomas (PGIM). MATERIAL AND
methodsThe Surveillance, Epidemiology, and End Results database (1973-2004) was queried.
resultsOverall, 659 cases of PGIM were identified. The annual incidence of PGIM was approximately 0.47 cases per million in 2000. Overall median survival time was 17 months. Tumors were identified in the oral-nasopharynx (32.8%), anal canal (31.4%), rectum (22.2%), esophagus (5.9%), stomach (2.7%), small bowel (2.3%), gallbladder (1.4%), and large bowel (0.9%). Univariate analysis demonstrated age, tumor location, stage, surgery, and lymph node status were significant predictors of improved survival. MST has not been reached for tumors located in the large bowel, while tumors located in the stomach demonstrated the shortest median survival (5 months). Improvement in MST was observed for those patients undergoing surgical resection. The presence of lymph node involvement conferred a poorer prognosis. Multivariate analysis of the cohort identified that location, advanced tumor stage, failure to undertake surgical resection, positive lymph node status, and age were all independent predictors of poorer outcome.
conclusionPGIM occurs most often in the oral-nasopharynx and anal canal. Surgical extirpation is the only identifiable treatment modality that significantly improves survival.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.