Evidence map›Paper›PMID 18058067›Full record

ReviewThe journal of headache and pain2007

Genetics of migraine and pharmacogenomics: some considerations.

Maria Piane, Patrizia Lulli, Ivano Farinelli, Simona Simeoni, Sergio De Filippis, Francesca Romana Patacchioli, Paolo Martelletti

Abstract readReview
In one paragraph

Review in The journal of headache and pain, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Establishment of a biorepository for migraine research: the experience of Interinstitutional Multidisciplinary BioBank (BioBIM).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013
    Article
  14. Preventive agents for migraine: focus on the antiepileptic drugs.Journal of central nervous system disease · 2012
    Article
  15. Future drugs for migraine.Internal and emergency medicine · 2009
    Review
  16. From migraine to stroke.Internal and emergency medicine · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria PianeDepartment of Diagnostic Sciences, Medical Genetics Section, 2nd School of Medicine, University of Rome La Sapienza, I-00185, Rome, Italy. maria.piane@uniroma1.it
Patrizia Lulli
Ivano Farinelli
Simona Simeoni
Sergio De Filippis
Francesca Romana Patacchioli
Paolo Martelletti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine is a complex disorder caused by a combination of genetic and environmental factors. Although family and twin studies show that there is a genetic component in migraine, no genes predisposing to common forms of the disorder, migraine with and without aura, have been identified. Patients with migraine respond differently to a given drug administered. The efficacy of therapy and the occurrence of adverse drug response are a consequence of individual variability. Genetic profiling of predisposition to migraine should facilitate the development of more effective diagnostic and therapeutic applications. The development of International Hap Map project could provide a powerful tool for identification of the candidate genes in this complex disease and pharmacogenomics research could be the promise for individualized treatments and prevention of adverse drug response.

Indexed as

Genetic Predisposition to DiseasePharmacogeneticsAnalgesicsHumansMigraine DisordersAnalgesics

Identifiers

PMID18058067
PMCPMC2779399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.