Evidence map›Paper›PMID 18057169›Full record

ReviewPostgraduate medical journal2007

Gene therapy in head and neck cancer: a review.

E Chisholm, U Bapat, C Chisholm, G Alusi, G Vassaux

Abstract readReview
In one paragraph

Review in Postgraduate medical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Multi-modality imaging for precise intra-arterial delivery of mRNA, AAVs, and antibodies to the head and neck area in mice.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo.Journal of controlled release : official journal of the Controlled Release Society · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Gene therapy.Oral diseases · 2014
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

E ChisholmMolecular Oncology, Cancer Research UK, Barts and The London NHS Trust, London, UK. edwardchisholm@doctors.org.uk
U Bapat
C Chisholm
G Alusi
G Vassaux

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene therapy for cancer is a rapidly evolving field with head and neck squamous cell cancer being one of the more frequently targeted cancer types. The number of clinical trials in the UK is growing and there is already a commercially available agent in China. Various gene therapy strategies along with delivery mechanisms for targeting head and neck cancer are reviewed.

Indexed as

Carcinoma, Squamous CellGenetic TherapyGenetic VectorsHead and Neck NeoplasmsHumans

Identifiers

PMID18057169
PMCPMC2750919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.