Evidence map›Paper›PMID 18057126›Full record

ArticleJournal of clinical microbiology2008

Evaluation of the one-step multiplex real-time reverse transcription-PCR ProFlu-1 assay for detection of influenza A and influenza B viruses and respiratory syncytial viruses in children.

Jérôme Legoff, Rachid Kara, Florence Moulin, Ali Si-Mohamed, Anne Krivine, Laurent Bélec, Pierre Lebon

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Rapid diagnosis of influenza: state of the art.Clinics in laboratory medicine · 2014
    Review
  5. Laboratory diagnosis of viral infection.Handbook of clinical neurology · 2014
    Review
  6. What is the role of newer molecular tests in the management of CAP?Infectious disease clinics of North America · 2013
    Review
  7. Article
  8. Article
  9. Strengths and weaknesses of FDA-approved/cleared diagnostic devices for the molecular detection of respiratory pathogens.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011
    Article
  10. Molecular diagnosis of viral respiratory infections.Current infectious disease reports · 2011
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Recent advances in diagnostic microbiology.Seminars in hematology · 2009
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jérôme LegoffLaboratoire de Microbiologie, Hôpital Européen Georges Pompidou, and Université Paris Descartes, Paris, France. jerome.le-goff@sls.aphp.fr.
Rachid Kara
Florence Moulin
Ali Si-Mohamed
Anne Krivine
Laurent Bélec
Pierre Lebon
Université Paris Cité · FRHôpital Saint-Vincent-de-Paul · FRHôpital Cochin · FRHôpital Européen Georges-Pompidou · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the one-step multiplex real-time reverse transcription-PCR ProFlu-1 assay for the detection of influenza A and influenza B viruses and respiratory syncytial viruses from 353 pediatric nasopharyngeal aspirates. As assessed by comparison with the results of immunofluorescence testing and cell culture, the specificity and the sensitivity of the ProFlu-1 assay ranged from 97% to 100%. In addition, the ProFlu-1 assay amplified 9% of samples not detected by conventional methods.

Indexed as

AdolescentChildChild, PreschoolFluorescent Antibody TechniqueHumansInfantInfant, NewbornInfluenza A virusInfluenza B virusInfluenza, HumanPharynxRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityVirus Cultivation

Identifiers

PMID18057126
PMCPMC2238076
OpenAlexW2124682865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.