ArticleDiabetes care2008
Diabetes-related complications, glycemic control, and falls in older adults.
Article in Diabetes care, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 190 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Hypoglycemia and Insulin Errors in Barnes-Jewish Hospital Inpatients
Leveraging the Power of the EMR: Using a Real Time Prediction Model to Decrease Inpatient Hypoglycemic Events
Who cites it
190 citing papers in PubMed, 6 syntheses or guidelines pooled it, 483 citations in OpenAlex.
- Risk factors for falls in older adults with diabetes mellitus: systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- A Concise and Systematic Review on Non-Invasive Glucose Monitoring for Potential Diabetes Management.Biosensors · 2022Pooled it
- Influence of glycemic control and hypoglycemia on the risk of fracture in patients with diabetes mellitus: a systematic review and meta-analysis of observational studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Pooled it
- Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2019Guideline
- Elderly patients with diabetes experience a lower rate of nocturnal hypoglycaemia with insulin degludec than with insulin glargine: a meta-analysis of phase IIIa trials.Drugs & aging · 2013Pooled it
- Bone health and type 2 diabetes mellitus: a systematic review.Physiotherapy Canada. Physiotherapie Canada · 2011Pooled it
- Effects of Canagliflozin on Fracture Risk in Patients With Type 2 Diabetes Mellitus.The Journal of clinical endocrinology and metabolism · 2016Trial
- Functional Impairments Mediate Association Between Clinical Fracture Risk and Type 2 Diabetes Mellitus in Older Women.Journal of the American Geriatrics Society · 2015Trial
- Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged ≥ 65 years) with inadequately controlled type 2 diabetes mellitus.Clinical interventions in aging · 2013Trial
- Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial.Diabetes care · 2012Trial
- Metabolic dysfunction-associated steatotic liver disease is associated with higher bone mineral density: results from NHANES.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Prevalence, risk factors and adverse health outcomes of osteosarcopenia in middle-aged and older adults with type 2 diabetes mellitus-a scoping review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Review
- Elevated fracture risk in a Danish cohort with type 2 diabetes mellitus and microvascular diseases.JBMR plus · 2026Article
- Safety of SGLT2 inhibitors versus DPP-4 inhibitors in super-elderly patients (≥ 80 years) with type 2 diabetes: a propensity score-matched cohort study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Impaired Bone Density and Quality in Type 1 Diabetes Mellitus: Prevalence and Key Clinical Correlations.Journal of clinical medicine · 2026Article
- Trajectories of chronic disease burden, depressive symptoms, and functional limitations related to falls in middle-aged and older adults: a matched longitudinal study.Frontiers in aging neuroscience · 2026Article
- 4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Relationship between sleep duration and falls in older Mexican Americans: Sex differences in a longitudinal study.Journal of psychosomatic research · 2025Article
- FallskipGeriatrics (Basel, Switzerland) · 2025Article
- The effects of type 1 and type 2 diabetes mellitus on bone health in chronic kidney disease.Nature reviews. Endocrinology · 2025Review
130 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
Abstract
objectiveOlder adults with type 2 diabetes are more likely to fall, but little is known about risk factors for falls in this population. We determined whether diabetes-related complications or treatments are associated with risk of falls in older diabetic adults. RESEARCH DESIGN AND
methodsIn the Health, Aging, and Body Composition cohort of well-functioning older adults, participants reported falls in the previous year at annual visits. Odds ratios (ORs) for more frequent falls among 446 diabetic participants whose mean age was 73.6 years, with an average follow-up of 4.9 years, were estimated with continuation ratio models.
resultsIn the first year, 23[corrected]% reported falling; 22, 26, 30[corrected], and 31[corrected]% fell in subsequent years. In adjusted models, reduced peroneal nerve response amplitude (OR 1.50 -95% CI 1.07-2.12], worst quartile versus others); higher cystatin-C, a marker of reduced renal function (1.38 [1.11-1.71], for 1 SD increase); poorer contrast sensitivity (1.41 [0.97-2.04], worst quartile versus others); and low A1C in insulin users (4.36 [1.32-14.46], A1C <or=6 vs. >8%) were associated with risk of falls. In those using oral hypoglycemic medications but not insulin, low A1C was not associated with risk of falls (1.29 [0.65-2.54], A1C <or=6 vs. >8%). Adjustment for physical performance explained some, but not all, of these associations.
conclusionsIn older diabetic adults, reducing diabetes-related complications may prevent falls. Achieving lower A1C levels with oral hypoglycemic medications was not associated with more frequent falls, but, among those using insulin, A1C <or=6% increased risk of falls.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.