Trial reportBMJ (Clinical research ed.)2008
Influences on older people's decision making regarding choice of topical or oral NSAIDs for knee pain: qualitative study.
Trial report in BMJ (Clinical research ed.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Clinical Practice Guidelines for Topical NSAIDs in the Treatment of Sports Injuries.Journal of evidence-based medicine · 2025Guideline
- Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study.BMJ (Clinical research ed.) · 2008Trial
- Assessment of Preferences in Taking Painkillers among Students of Medicine, Dentistry, and Pharmacy: A Pilot Study.Healthcare (Basel, Switzerland) · 2024Article
- Factors Related to the Use of Topical vs. Oral NSAIDs for Sprains, Strains, and Contusions in a Senior Population: A Retrospective Analysis of Administrative Claims Data.Drugs & aging · 2018Article
- What are patients' knowledge, expectation and experience of radial extracorporeal shockwave therapy for the treatment of their tendinopathies? A qualitative study.Journal of foot and ankle research · 2018Article
- Physiotherapy management of knee osteoarthritis in Nigeria-A survey of self-reported treatment preferences.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2017Article
- Understanding the use of over-the-counter pain treatments in adolescents with chronic pain.Canadian journal of pain = Revue canadienne de la douleur · 2017Article
- The attitudes of owners and veterinary professionals in the United Kingdom to the risk of adverse events associated with using non-steroidal anti-inflammatory drugs (NSAIDs) to treat dogs with osteoarthritis.Preventive veterinary medicine · 2016Article
- Patient reported barriers and facilitators to using a self-management booklet for hip and knee osteoarthritis in primary care: results of a qualitative interview study.BMC family practice · 2013Article
- What can qualitative research do for randomised controlled trials? A systematic mapping review.BMJ open · 2013Article
- Development and initial evaluation of a treatment decision dashboard.BMC medical informatics and decision making · 2013Article
- Osteoarthritis guidelines: a progressive role for topical nonsteroidal anti-inflammatory drugs.Journal of multidisciplinary healthcare · 2013Article
- Inequalities in primary care management of knee pain and disability in older adults: an observational cohort study.Rheumatology (Oxford, England) · 2011Article
- Nonsteroidal anti-inflammatory drug gastropathy: new avenues for safety.Clinical interventions in aging · 2011Review
- Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury.International journal of clinical practice · 2010Review
- Management of chronic knee pain: a survey of patient preferences and treatment received.BMC musculoskeletal disorders · 2008Article
- Adverse Drug Reactions in Elderly People: The challenge of safer prescribing.BMJ (Clinical research ed.) · 2008Article
- Osteoarthritis of the knee in primary care.BMJ (Clinical research ed.) · 2008Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo explore the factors that influence older people's decision making regarding use of topical or oral ibuprofen for their knee pain.
designQualitative interview study nested within a randomised controlled trial and a patient preference study that compared advice to use oral or topical non-steroidal anti-inflammatory drugs (NSAIDs) for knee pain in older people.
setting11 general practices.
participants30 people aged > or =50 with knee pain.
resultsParticipants' decision making was influenced by their perceptions of the associated risk of adverse effects, presence of other illness, nature of their pain, advice received, and practicality. Although participants' understanding of how the medications worked was sometimes poor their decision making about the use of NSAIDs seemed logical and appropriate. Participants' model for treatment was to use topical NSAIDs for mild, local, and transient pain and oral NSAIDs for moderate to severe, generalised, and constant pain (in the absence of other more serious illness or risk of adverse effects). Participants showed marked tolerance and normalisation of adverse effects.
conclusionParticipants had clear ideas about the appropriate use of oral and topical NSAIDs. Taking such views into account when prescribing may improve adherence, judgment of efficacy, and the doctor-patient relationship. Tolerance and normalisation of adverse effects in these patients indicate that closer monitoring of older people who use NSAIDs might be needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.