ArticlePlant physiology2008
UV-B signaling pathways with different fluence-rate response profiles are distinguished in mature Arabidopsis leaf tissue by requirement for UVR8, HY5, and HYH.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers.
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Who cites it
123 citing papers in PubMed.
- Phosphorylation of the plant photoreceptor UVR8 regulates its dimer/monomer status and enhances UV-B signaling across species.The Plant cell · 2026Article
- OsCPK12-OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Evolutionarily conserved but not indispensable for survival: plastic UV RESISTANCE LOCUS8 functionality in Marchantia polymorpha under laboratory and field conditions.Journal of experimental botany · 2026Article
- Transcription factors interact with Arabidopsis UVR8 photoreceptor at distinct sites to COP1 and RUP proteins.The Plant journal : for cell and molecular biology · 2026Article
- Involvement of the Light Signalling Components HY5 and BIC1,2 and SPA1 in Plant Responses to Elevated Daytime UV-B Doses.International journal of molecular sciences · 2026Article
- Integration of light quality signals regulates ABA abundance and stomatal movements during seedling establishment.The New phytologist · 2026Article
- Flavonoid pathway intermediates implicate UVR8 in functions beyond canonical UV-B signaling.Nature communications · 2025Article
- UV-B Irradiation Does Not Promote Flowering inPlant direct · 2025Article
- Plant stress and proteomics in medicinal plants.Frontiers in plant science · 2025Review
- Adaptive responses of plants to light stress: mechanisms of photoprotection and acclimation. A review.Frontiers in plant science · 2025Review
- Requirement of two simultaneous environmental signals for activation of ArabidopsisPlant signaling & behavior · 2024Article
- Circadian and environmental signal integration in a natural population ofProceedings of the National Academy of Sciences of the United States of America · 2024Article
- MicroRNA164 Affects Plant Responses to UV Radiation in Perennial Ryegrass.Plants (Basel, Switzerland) · 2024Article
- OsbZIP18 Is a Positive Regulator of Phenylpropanoid and Flavonoid Biosynthesis under UV-B Radiation in Rice.Plants (Basel, Switzerland) · 2024Article
- PSI Photoinhibition and Changing COAntioxidants (Basel, Switzerland) · 2023Article
- Article
- Light signaling as cellular integrator of multiple environmental cues in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Review
- ELONGATED HYPOCOTYL5 (HY5) and HY5 HOMOLOGUE (HYH) maintain shade avoidance suppression in UV-B.The Plant journal : for cell and molecular biology · 2023Article
- MYB30 and MYB14 form a repressor-activator module with WRKY8 that controls stilbene biosynthesis in grapevine.The Plant cell · 2023Article
- Functions of nitric oxide-mediated post-translational modifications under abiotic stress.Frontiers in plant science · 2023Review
63 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
UV-B signaling is an important but poorly understood aspect of light responsiveness in plants. Arabidopsis (Arabidopsis thaliana) UV RESISTANCE LOCUS8 (UVR8) is a recently identified UV-B-specific signaling component that regulates UV-protective responses. Using the uvr8 mutant, we defined genetically distinct UVR8-dependent and UVR8-independent pathways that stimulate different sets of genes in mature Arabidopsis leaf tissue. Both pathways operate at 1 micromol m(-2) s(-1) UV-B and above, but the UVR8-dependent pathway is able to stimulate UV-protective genes even in response to 0.1 micromol m(-2) s(-1) UV-B. Both pathways function in mutants lacking phytochromes, cryptochromes, or phototropins. Genes encoding the ELONGATED HYPOCOTYL5 (HY5) and HY5 HOMOLOG (HYH) transcription factors are induced at low UV-B fluence rates (0.1 micromol m(-2) s(-1)). Experiments with hy5 and hyh mutants reveal that both these factors mediate responses of the UVR8-dependent pathway, acting with partial or complete redundancy to stimulate expression of particular genes. Furthermore, evidence is presented that all UVR8 pathway genes are likely to be regulated by HY5/HYH and that these transcription factors do not mediate UV-B responses independent of UVR8. Finally, we highlight the functions of HY5 and HYH in UV protection and show that HY5 plays the more critical role. This research provides evidence that, in UV-B signaling, UVR8, HY5, and HYH act together in a photoregulatory pathway and demonstrates a new role for HYH in UV-B responses.
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