ArticleAutonomic neuroscience : basic & clinical2008
Diminished baroreflex-induced vasoconstriction following alpha-2 adrenergic receptor blockade in humans.
Article in Autonomic neuroscience : basic & clinical, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
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- Dietary supplement increases plasma norepinephrine, lipolysis, and metabolic rate in resistance trained men.Journal of the International Society of Sports Nutrition · 2009Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The relative contribution of alpha adrenergic receptor subtypes in the transduction of sympathetic nerve activity (SNA) during carotid baroreflex (CBR) engagement is not well understood. Therefore, we compared the hemodynamic consequence of CBR-mediated sympatho-excitation via neck pressure (NP) before and after alpha-2 adrenergic blockade with intra-arterial yohimbine. Leg blood flow was measured using 2D and Doppler ultrasound, and arterial blood pressure was determined directly. NP caused the expected vasoconstriction, and this response was significantly reduced (by 50-60%) when NP was repeated after yohimbine. These data indicate that alpha-2 adrenergic receptors contribute significantly to CBR-induced vasoconstriction in the human leg under resting conditions.
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Registered trials
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