ReviewProgress in neurobiology2008
Vasopressin: behavioral roles of an "original" neuropeptide.
Review in Progress in neurobiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
207 citing papers in PubMed, 1 synthesis or guideline pooled it, 490 citations in OpenAlex.
- The role of neuropeptides in suicidal behavior: a systematic review.BioMed research international · 2013Pooled it
- The novel vasopressin receptor (V1aR) antagonist SRX246 reduces anxiety in an experimental model in humans: a randomized proof-of-concept study.Psychopharmacology · 2021Trial
- Vasopressin modulates social recognition-related activity in the left temporoparietal junction in humans.Translational psychiatry · 2011Trial
- Vasopressin modulates medial prefrontal cortex-amygdala circuitry during emotion processing in humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Trial
- Supplementation of a DHA commercial lipid emulsion in diets for tropical gar (Atractosteus tropicus) larvae: effects on growth, cannibalistic behavior, digestive enzyme activity, and aggressiveness-related genes.Fish physiology and biochemistry · 2026Article
- Arginine-vasopressin systems in autistic phenotype schizophrenia: effect of a genetic variant of AVPR1a and AVPR1b.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Associations between anterior hypothalamic subunits and ADHD and autistic traits revealed by deep learning MRI segmentation.Discover mental health · 2026Article
- Sexual aggression and prenatal stress lead to poor maternal care and aggressive behaviour in male Wistar rat offspring.IBRO neuroscience reports · 2026Article
- Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution.Angewandte Chemie (International ed. in English) · 2026Article
- Effects of combined prenatal exposure to air pollution and maternal stress on social behavior and oxytocin and vasopressin systems in male and female mice.Journal of neuroendocrinology · 2026Article
- Nonlinear and sex-specific effects of V1aR deletion on juvenile social behavior.Frontiers in endocrinology · 2026Article
- Connectivity and phenotype of vasopressin 1a receptor cells in the lateral septum.bioRxiv : the preprint server for biology · 2025Article
- Effects of combined prenatal exposure to air pollution and maternal stress on social behavior and oxytocin and vasopressin systems in male and female mice.bioRxiv : the preprint server for biology · 2025Article
- Unraveling Evolutionary Insights into AVT Peptide Conservation and Antimicrobial Motif Prediction Across Taxa.International journal of molecular sciences · 2025Article
- Oxytocin, Vasopressin and Stress: A Hormetic Perspective.Current issues in molecular biology · 2025Review
- Sex difference in the effects of ventral pallidum vasopressin 1a receptor partial knockdown on social behavior in mice.Hormones and behavior · 2025Article
- Beyond Latency: ChronicBiomedicines · 2025Review
- Vasopressin and oxytocin excite BNST neurons via oxytocin receptors, which reduce anxious arousal.Cell reports · 2025Article
- In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism.BMC genomics · 2025Article
- Neuropeptide receptor distributions in male and femaleBiology letters · 2025Article
147 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Vasopressin (Avp) is mainly synthesized in the magnocellular cells of the hypothalamic supraoptic (SON) and paraventricular nuclei (PVN) whose axons project to the posterior pituitary. Avp is then released into the blood stream upon appropriate stimulation (e.g., hemorrhage or dehydration) to act at the kidneys and blood vessels. The brain also contains several populations of smaller, parvocellular neurons whose projections remain within the brain. These populations are located within the PVN, bed nucleus of the stria terminalis (BNST), medial amygdala (MeA) and suprachiasmatic nucleus (SCN). Since the 1950s, research examining the roles of Avp in the brain and periphery has intensified. The development of specific agonists and antagonists for Avp receptors has allowed for a better elucidation of its contributions to physiology and behavior. Anatomical, pharmacological and transgenic, including "knockout," animal studies have implicated Avp in the regulation of various social behaviors across species. Avp plays a prominent role in the regulation of aggression, generally of facilitating or promoting it. Affiliation and certain aspects of pair-bonding are also influenced by Avp. Memory, one of the first brain functions of Avp that was investigated, has been implicated especially strongly in social recognition. The roles of Avp in stress, anxiety, and depressive states are areas of active exploration. In this review, we concentrate on the scientific progress that has been made in understanding the role of Avp in regulating these and other behaviors across species. We also discuss the implications for human behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.