ArticleJournal of materials science. Materials in medicine2008
Preparation of porous apatite granules from calcium phosphate cement.
Article in Journal of materials science. Materials in medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 60 citations in OpenAlex.
- Incorporating the Antioxidant Fullerenol into Calcium Phosphate Bone Cements Increases Cellular Osteogenesis without Compromising Physical Cement Characteristics.Advanced engineering materials · 2023Article
- Biomedical Radioactive Glasses for Brachytherapy.Materials (Basel, Switzerland) · 2021Review
- Development prospects of curable osteoplastic materials in dentistry and maxillofacial surgery.Heliyon · 2020Review
- Human iPSC-derived iMSCs improve bone regeneration in mini-pigs.Bone research · 2019Article
- Nanostructured platforms for the sustained and local delivery of antibiotics in the treatment of osteomyelitis.Critical reviews in therapeutic drug carrier systems · 2015Review
- The composite of bone marrow concentrate and PRP as an alternative to autologous bone grafting.PloS one · 2014Article
- Self-setting calcium orthophosphate formulations.Journal of functional biomaterials · 2013Article
- Calcium Orthophosphate-Based Bioceramics.Materials (Basel, Switzerland) · 2013Review
- Direct scaffolding of biomimetic hydroxyapatite-gelatin nanocomposites using aminosilane cross-linker for bone regeneration.Journal of materials science. Materials in medicine · 2012Article
- Calcium orthophosphates as bioceramics: state of the art.Journal of functional biomaterials · 2010Article
- The progress of early phase bone healing using porous granules produced from calcium phosphate cement.European journal of medical research · 2010Article
- Review
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1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
A versatile method for preparing spherical, micro- and macroporous (micro: 2-10 and macro: 150-550 microm pores), carbonated apatitic calcium phosphate (Ap-CaP) granules (2-4 mm in size) was developed by using NaCl crystals as the porogen. The entire granule production was performed between 21 and 37 degrees C. A CaP cement powder, comprising alpha-Ca3(PO4)2 (61 wt.%), CaHPO4 (26%), CaCO3 (10%) and precipitated hydroxyapatite, Ca10(PO4)6(OH)2 (3%), was dry mixed with NaCl crystals varying in size from 420 microm to 1 mm. Cement powder (35 wt.%) and NaCl (65 wt.%) mixture was kneaded with an ethanol-Na2HPO4 initiator solution, and the formed dough was immediately agitated on an automatic sieve shaker for a few minutes to produce the spherical granules. Embedded NaCl crystals were then leached out of the granules by soaking them in deionized water. CaP granules were micro- and macroporous with a total porosity of 50% or more. Granules were composed of carbonated, poorly crystallized, apatitic CaP phase. These were the first spherical and porous CaP granules ever produced from a self-setting calcium phosphate cement. The granules reached their final handling strength at the ambient temperature through the cement setting reaction, without having a need for sintering.
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