Evidence map›Paper›PMID 18049290›Full record

SynthesisJournal of the American Academy of Child and Adolescent Psychiatry2007

Cognitive-behavioral therapy for adolescent depression: a meta-analytic investigation of changes in effect-size estimates.

Jesse B Klein, Rachel H Jacobs, Mark A Reinecke

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of the American Academy of Child and Adolescent Psychiatry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  5. Barriers to managing child and adolescent mental health problems: a systematic review of primary care practitioners' perceptions.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jesse B KleinDepartment of Psychiatry, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. jesseklein@northwestern.edu
Rachel H Jacobs
Mark A Reinecke

Funding

Perfectionism in adolescents with depressionF31MH075308 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JACOBS, RACHEL H · 2006 to 2008
$88k
NIMH NIH HHS F31 MH075308NIMH NIH HHS F31MH075308
6 · The paper itself

Abstract

objectiveTo explicate differences between early and recent meta-analytic estimates of the effects of cognitive-behavioral therapy (CBT) for adolescent depression.

methodMeta-analytic procedures were used to investigate whether methodological characteristics moderated mean effect sizes among 11 randomized, controlled trials of CBT focusing on adolescents meeting diagnostic criteria for unipolar depression.

resultsCumulative meta-analyses indicated that effects of CBT have decreased from large effects in early trials, and confidence intervals have become narrower. Effect sizes were significantly smaller among studies that used intent-to-treat analytic strategies, compared CBT to active treatments, were conducted in clinical settings, and featured greater methodological rigor based on CONSORT (Consolidated Standards of Reporting Trials) criteria. The mean posttreatment effect size of 0.53 was statistically significant.

conclusionsDifferences in estimates of the efficacy of CBT for depressed adolescents may stem from methodological differences between early and more recent investigations. Overall, results support the effectiveness of CBT for the treatment of adolescent depression.

Indexed as

AdolescentCognitive Behavioral TherapyHumansMajor Depressive DisorderTreatment Outcome

Identifiers

PMID18049290
PMCPMC2270481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.