Evidence map›Paper›PMID 18048614›Full record

ArticleTobacco control2007

Use of nicotine replacement therapy to reduce or delay smoking but not to quit: prevalence and association with subsequent cessation efforts.

Douglas E Levy, Anne N Thorndike, Lois Biener, Nancy A Rigotti

Abstract read
In one paragraph

Article in Tobacco control, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Over-the-counter nicotine replacement therapy: can its impact on smoking cessation be enhanced?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2008
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Douglas E LevyInstitute for Health Policy, Massachusetts General Hospital, 50 Staniford Street, 9th floor, Boston, MA 02114, USA. douglas_levy@hms2.harvard.edu
Anne N Thorndike
Lois Biener
Nancy A Rigotti

Funding

Smoking Trajectories amid Waning State Program BudgetsR01CA086257 · NCI · UNIVERSITY OF MASSACHUSETTS BOSTON · PI BIENER, LOIS BARBARA · 2000 to 2008
$6.1M
Smoking Cessation Interventions for Health Care SettingsK24HL004440 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI RIGOTTI, NANCY A · 2000 to 2009
$1.5M
NCI NIH HHS R01 CA086257NCI NIH HHS R01-CA86257NHLBI NIH HHS K24 HL004440NHLBI NIH HHS K24-HL04440
6 · The paper itself

Abstract

objectiveTo assess the prevalence of nicotine replacement therapy (NRT) use for purposes other than quitting smoking and examine the relation of this non-standard NRT use (NSNRT) with subsequent smoking cessation efforts.

designA population based cohort study of adult smokers who were interviewed by telephone at baseline (2001-2) and at two year follow-up. The association between NSNRT use to cut down on smoking or to delay smoking before baseline and cessation attempts and smoking outcomes at two year follow-up was assessed using logistic regression to adjust for multiple potential confounding factors.

settingMassachusetts, USA. SUBJECTS: 1712 adult smokers in Massachusetts who were selected using a random digit dial telephone survey.

main outcome measuresQuit attempt in 12 months before follow-up, NRT use at quit attempt in 12 months before follow-up, smoking cessation by follow-up, or 50% reduction in cigarettes smoked per day between baseline and follow-up.

results18.7% of respondents reported ever having used NSNRT. In a multiple logistic regression analysis, there was no statistically significant association between past NSNRT use and quit attempts (OR(cut down) = 0.89, 95% CI 0.59 to 1.33; OR(delay) = 1.29, 95% CI 0.73 to 2.29), smoking cessation (OR(cut down) = 0.74, 95% CI 0.43 to 1.24; OR(delay) = 1.22, 95% CI 0.60 to 2.50) or 50% reduction in cigarettes smoked per day (OR(cut down) = 0.93, 95% CI 0.62 to 1.38; OR(delay) = 0.80, 95% CI 0.43 to 1.49) at follow-up. Past use of NRT to cut down on cigarettes was associated with use of NRT at a follow-up quit attempt (OR(cut down) = 2.28, 95% CI 1.50 to 3.47) but past use of NRT to delay smoking was not (OR(delay) = 1.25, 95% CI 0.67 to 2.34).

conclusionsUse of NRT for reasons other than quitting smoking may be more common than was previously estimated. This population based survey finds no strong evidence that NRT use for purposes other than quitting smoking is either harmful or helpful.

Indexed as

AdolescentAdultAgedFemaleFollow-Up StudiesHealth BehaviorHumansMaleMassachusettsMiddle AgedNicotineNicotinic AgonistsPrevalenceProspective StudiesSmokingSmoking CessationNicotineNicotinic Agonists

Identifiers

PMID18048614
PMCPMC2807189

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.