ArticleThe Journal of biological chemistry2008
Modulation of yeast Sln1 kinase activity by the CCW12 cell wall protein.
Article in The Journal of biological chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Searching for Osmosensing Determinants in Poplar Histidine-Aspartate Kinases.International journal of molecular sciences · 2023Article
- The yeast two-component SLN1 branch of the HOG pathway and the scaffolding activity of Pbs2 modulate the response to endoplasmic reticulum stress induced by tunicamycin.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
- Improving the functionality of surface-engineered yeast cells by altering the cell wall morphology of the host strain.Applied microbiology and biotechnology · 2021Article
- The two transmembrane regions of Candida albicans Dfi1 contribute to its biogenesis.Biochemical and biophysical research communications · 2017Article
- Up-regulation of NCED3 and ABA biosynthesis occur within minutes of a decrease in leaf turgor but AHK1 is not required.Journal of experimental botany · 2017Article
- Functional Divergence of Poplar Histidine-Aspartate Kinase HK1 Paralogs in Response to Osmotic Stress.International journal of molecular sciences · 2016Article
- Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010).Antimicrobial agents and chemotherapy · 2015Article
- Role of the putative osmosensor Arabidopsis histidine kinase1 in dehydration avoidance and low-water-potential response.Plant physiology · 2013Article
- Review
- Response to hyperosmotic stress.Genetics · 2012Review
- Article
- Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.Genetics · 2011Review
- Association of the Skn7 and Yap1 transcription factors in the Saccharomyces cerevisiae oxidative stress response.Eukaryotic cell · 2011Article
- Characterization of the conserved phosphorylation site in the Aspergillus nidulans response regulator SrrA.Current genetics · 2011Article
- The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections.BMC genomics · 2011Article
- Fungal Skn7 stress responses and their relationship to virulence.Eukaryotic cell · 2011Review
- A two-component histidine kinase, MoSLN1, is required for cell wall integrity and pathogenicity of the rice blast fungus, Magnaporthe oryzae.Current genetics · 2010Article
- Genetic and biochemical analysis of the SLN1 pathway in Saccharomyces cerevisiae.Methods in enzymology · 2010Article
- Kinetic studies of the yeast His-Asp phosphorelay signaling pathway.Methods in enzymology · 2010Article
- Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae.Biochemistry · 2009Article
Corrections and comments
- Erratum issuedNarang, Sandhya S [corrected to Shankarnarayan, Sandhya]
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The yeast Sln1p sensor kinase is best known as an osmosensor involved in the regulation of the hyperosmolarity glycerol mitogen-activated protein kinase cascade. Down-regulation of Sln1 kinase activity occurs under hypertonic conditions and leads to phosphorylation of the Hog1p mitogen-activated protein kinase and increased osmotic stress-response gene expression. Conditions leading to kinase up-regulation include osmotic imbalance caused by glycerol retention in the glycerol channel mutant, fps1 (Tao, W., Deschenes, R. J., and Fassler, J. S. (1999) J. Biol. Chem. 274, 360-367). The hypothesis that Sln1p kinase activity is responsive to turgor was first suggested by the increased Sln1p kinase activity in mutants lacking Fps1p in which glycerol accumulation leads to water uptake. Also consistent with the turgor hypothesis is the observation that reduced turgor caused by treatment of cells with nystatin, a drug that increases membrane permeability and causes cell shrinkage, reduced Sln1p kinase activity (Tao, W., Deschenes, R. J., and Fassler, J. S. (1999) J. Biol. Chem. 274, 360-367; Reiser, V., Raitt, D. C., and Saito, H. (2003) J. Cell Biol. 161, 1035-1040). The turgor hypothesis is revisited here in the context of the identification and characterization of the cell wall gene, CCW12, as a determinant of Sln1p activity. Results of this analysis suggest that the activity of the plasma membrane localized Sln1p is affected by the presence or absence of specific outer cell wall proteins and that this effect is independent of turgor.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.