ArticleAmerican journal of hypertension2007
Ethnic differences in the association of birth weight and blood pressure: the Georgia cardiovascular twin study.
Article in American journal of hypertension, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Associations of antenatal micronutrient supplementation with adolescent blood pressure: evidence from a 14-year follow-up study of a randomized controlled trial.BMC public health · 2025Trial
- Racial differences of early vascular aging in children and adolescents.Pediatric nephrology (Berlin, Germany) · 2021Review
- Racial Disparities in Blood Pressure Trajectories of Preterm Children: The Role of Family and Neighborhood Socioeconomic Status.American journal of epidemiology · 2017Article
- Low Birth Weight as a Predictor of Cardiovascular Risk Factors in Childhood and Adolescence? The PEP Family Heart Study.International journal of preventive medicine · 2015Article
- Low level maternal smoking and infant birthweight reduction: genetic contributions of GSTT1 and GSTM1 polymorphisms.BMC pregnancy and childbirth · 2012Article
- Origins of disparities in cardiovascular disease: birth weight, body mass index, and young adult systolic blood pressure in the national longitudinal study of adolescent health.Annals of epidemiology · 2011Article
- Maternal smoking, GSTM1 and GSTT1 polymorphism and susceptibility to adverse pregnancy outcomes.International journal of environmental research and public health · 2009Article
- Heritability of cardiovascular risk factors in a Brazilian population: Baependi Heart Study.BMC medical genetics · 2008Article
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Authors and funding
7 authors at 2 institutions in 4 countries.
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Abstract
backgroundAfrican Americans (AAs) not only have higher blood-pressure levels, but also an increased risk of low weight at birth, compared with European Americans (EAs). In light of fetal programming theories, it has been suggested that ethnic differences in blood pressure originate in utero. However, most previous studies in biethnic samples have not found a significant inverse association between birth weight and blood pressure in AAs.
methodsIn 562 EA and 465 AA adolescent twins of the Georgia Cardiovascular Twin Study, we investigated the potential ethnic difference in the association of blood pressure and birth weight, with the ability to control for potential confounding by familial factors.
resultsBlood-pressure levels were significantly higher in AAs compared to EAs, independent of birth weight (P < .01). After adjustment for parental factors and body mass index, the difference in systolic blood pressure per kg birth weight was -1.1 mm Hg (95% confidence interval, -2.7 to 0.48, P = .17) in EAs, and -2.5 mm Hg (95% confidence interval, -4.7 to -0.40, P = .02) in AAs. A significant ethnic interaction was revealed in paired analysis, where the inverse association remained in AAs, but not in EAs. Associations with diastolic blood pressure were generally weaker and nonsignificant.
conclusionsWe showed that low birth weight was associated with an elevated systolic blood pressure in AAs, independent of familial factors. The results also suggest that the association between birth weight and blood pressure may be more pronounced in AAs in adolescence.
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