Evidence map›Paper›PMID 18047701›Full record

ReviewGenome biology2007

Insertional mutagenesis strategies in zebrafish.

Sridhar Sivasubbu, Darius Balciunas, Adam Amsterdam, Stephen C Ekker

Open access · bronzeAbstract readReview
In one paragraph

Review in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Tipping the Scales With Zebrafish to Understand Adaptive Tumor Immunity.Frontiers in cell and developmental biology · 2021
    Review
  6. Zebrafish as a model for kidney function and disease.Pediatric nephrology (Berlin, Germany) · 2019
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Time for the zebrafish ENCODE.Journal of genetics · 2013
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Sridhar SivasubbuInstitute of Genomics and Integrative Biology, Council for Scientific and Industrial Research, Mall Road, Delhi 110007, India.
Darius Balciunas
Adam Amsterdam
Stephen C Ekker
University of Minnesota · USInstitute of Genomics and Integrative Biology · INMassachusetts Institute of Technology · US

Funding

INSERTIONAL MUTAGENESIS SCREENR01RR012589 · NCRR · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HOPKINS, NANCY H. · 1998 to 2005
$5.0M
Intron-based Mutagenic Transposons for ZebrafishR01DA014546 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI EKKER, STEPHEN CARL · 2001 to 2011
$3.5M
NCRR NIH HHS R01 RR012589NCRR NIH HHS RR012589NIDA NIH HHS DA14546NIDA NIH HHS R01 DA014546
6 · The paper itself

Abstract

We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches.

Indexed as

AnimalsDNA Transposable ElementsEmbryonic Stem CellsMutagenesis, InsertionalRetroviridaeZebrafishDNA Transposable Elements

Identifiers

PMID18047701
PMCPMC2106850
OpenAlexW2120572391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.