ReviewGenome biology2007
Manipulating the Xenopus genome with transposable elements.
Review in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice.Scientific reports · 2016Article
- Comprehensive transcriptome profiling and functional analysis of the frog (Bombina maxima) immune system.DNA research : an international journal for rapid publication of reports on genes and genomes · 2014Article
- Article
- The hitchhiker's guide to Xenopus genetics.Genesis (New York, N.Y. : 2000) · 2012Review
- Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis.Mobile DNA · 2011Article
- Xenopus: An emerging model for studying congenital heart disease.Birth defects research. Part A, Clinical and molecular teratology · 2011Review
- Development and initial characterization of a HAPPY panel for mapping the X. tropicalis genome.International journal of biological sciences · 2011Article
- Remobilization of Tol2 transposons in Xenopus tropicalis.BMC developmental biology · 2010Article
- Transgenesis in parasitic nematodes: building a better array.Trends in parasitology · 2009Article
- Transgenesis in Xenopus using the Sleeping Beauty transposon system.Developmental dynamics : an official publication of the American Association of Anatomists · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The study of amphibian embryogenesis has provided important insight into the mechanisms of vertebrate development. The frog Xenopus laevis has been an important model of vertebrate cell biology and development for many decades. Genetic studies in this organism are not practical because of the tetraploid nature of the genome and the long generation time of this species. Recently, a closely related frog, namely Xenopus tropicalis, has been proposed as an alternative system; it shares all of the physical characteristics that make X. laevis a useful model but has the advantage of a diploid genome and short generation time. The rapid accumulation of genetic resources for this animal and the success of pilot mutagenesis screens have helped propel this model system forward. Transposable elements will provide invaluable tools for manipulating the frog genome. These integration systems are ideally suited to transgenesis and insertional mutagenesis strategies in the frog. The high fecundity of the frog combined with the ability to remobilize transposon transgenes integrated into frog genome will allow large-scale insertional mutagenesis screens to be performed in laboratories with modest husbandry capacities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.