ReviewInternational journal of chronic obstructive pulmonary disease2006
Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management.
Review in International journal of chronic obstructive pulmonary disease, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Liver Disease and Prevalence of Liver Transplantation in Adults With ZZ Alpha-1 Antitrypsin Deficiency-A Meta-Analysis.Liver international communications · 2025Article
- New variants of alpha-1-antitrypsin: structural simulations and clinical expression.Respiratory research · 2022Article
- The Serpin Superfamily and Their Role in the Regulation and Dysfunction of Serine Protease Activity in COPD and Other Chronic Lung Diseases.International journal of molecular sciences · 2021Review
- Clinical considerations in individuals with αThe European respiratory journal · 2020Review
- Knowledge of Rare Respiratory Diseases among Paediatricians and Medical School Students.Journal of clinical medicine · 2020Article
- Case finding of Alpha-1 antitrypsin deficiency: never wasted time!Multidisciplinary respiratory medicine · 2018Article
- COPD in individuals with the PiMZ alpha-1 antitrypsin genotype.European respiratory review : an official journal of the European Respiratory Society · 2017Review
- Case-finding for alpha1-antitrypsin deficiency in Kazakh patients with COPD.Multidisciplinary respiratory medicine · 2017Article
- Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency?International journal of chronic obstructive pulmonary disease · 2017Article
- Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2012Review
- Rapid genotyping of alpha 1 antitrypsin deletion mutation (PI*Mmalton) using bi-directional PCR allele-specific amplification.Molecular biotechnology · 2010Article
- Screening for Alpha 1 antitrypsin deficiency in Tunisian subjects with obstructive lung disease: a feasibility report.Orphanet journal of rare diseases · 2009Article
- Article
- The impact of social contexts in testing for alpha-1 antitrypsin deficiency: the roles of physicians and others.Genetic testing and molecular biomarkers · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Alpha One International Registry (AIR), a multinational research program focused on alpha1-antitrypsin (AAT) deficiency, was formed in response to a World Health Organization recommendation. Each of the nearly 20 participating countries maintains a national registry of patients with AAT deficiency and contributes to an international database located in Malmö, Sweden. This database is designed to increase understanding of AAT deficiency. Additionally, AIR members are engaged in active, wide-ranging investigations to improve the diagnosis, monitoring, and treatment of the disease and meet biennially to exchange views and research findings. The fourth biennial meeting was held in Copenhagen, Denmark, on 2-3 June 2005. This review covers the wide range of AAT deficiency-related topics that were addressed encompassing advances in genetic characterization, risk factor identification, clinical epidemiology, inflammatory and signalling processes, therapeutic advances, and lung imaging techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.