ReviewClinical interventions in aging2006
Anti-aging therapy through fitness enhancement.
Review in Clinical interventions in aging, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Exercise-induced changes in plasma S-Klotho levels are associated with the obtained enhancements of heart rate variability in sedentary middle-aged adults: the FIT-AGEING study.Journal of physiology and biochemistry · 2024Trial
- Influence of daily beer or ethanol consumption on physical fitness in response to a high-intensity interval training program. The BEER-HIIT study.Journal of the International Society of Sports Nutrition · 2020Trial
- 24-weeks Pilates-aerobic and educative training to improve body fat mass in elderly Serbian women.Clinical interventions in aging · 2014Trial
- The Relationship Between Neurocognitive Function and Concussion in Women Professional Football Players: A Cross-Sectional Study.Sports (Basel, Switzerland) · 2025Article
- Effects of aging and resistance exercise on muscle strength, physiological properties, longevity proteins, and telomere length in SAMP8 mice.Biogerontology · 2025Article
- The role of different physical exercises as an anti-aging factor in different stem cells.Biogerontology · 2025Review
- Physical Exercise: A Promising Treatment Against Organ Fibrosis.International journal of molecular sciences · 2025Review
- Soccer (football) and brain health.Journal of neurology · 2024Review
- Cardiac Rehabilitation Increases Plasma Klotho Levels.Journal of clinical medicine · 2024Article
- Insights into Non-Exercise Physical Activity on Control of Body Mass: A Review with Practical Recommendations.Journal of functional morphology and kinesiology · 2023Review
- Exercise blood-drop metabolic profiling links metabolism with perceived exertion.Frontiers in molecular biosciences · 2022Article
- Evidencing the Influence of the COVID-19 Pandemic and Imposed Lockdown Measures on Fitness Status in Adolescents: A Preliminary Report.Healthcare (Basel, Switzerland) · 2021Article
- Male and Female Animals Respond Differently to High-Fat Diet and Regular Exercise Training in a Mouse Model of Hyperlipidemia.International journal of molecular sciences · 2021Article
- Estimation of Health-Related Physical Fitness Using Multiple Linear Regression in Korean Adults: National Fitness Award 2015-2019.Frontiers in physiology · 2021Article
- Klotho, Aging, and the Failing Kidney.Frontiers in endocrinology · 2020Review
- Factors Associated with Cardiorespiratory Fitness in a Swiss Working Population.Journal of sports medicine (Hindawi Publishing Corporation) · 2019Article
- Botulinum toxin (Botox) A for reducing the appearance of facial wrinkles: a literature review of clinical use and pharmacological aspect.Clinical, cosmetic and investigational dermatology · 2019Article
- Health-related quality of life in long-term survivors of colorectal cancer and its association with all-cause mortality: a German cohort study.BMC cancer · 2018Article
- Moderate aerobic exercise training decreases middle-aged induced pathologic cardiac hypertrophy by improving Klotho expression, MAPK signaling pathway, and oxidative stress status in Wistar rats.Iranian journal of basic medical sciences · 2018Article
- Exercise training as S-Klotho protein stimulator in sedentary healthy adults: Rationale, design, and methodology.Contemporary clinical trials communications · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical exercise is proposed as a highly effective means of treating and preventing the main causes of morbidity and mortality--most of which are associated with aging--in industrialized countries. Low physical fitness is an important risk factor for cardiovascular and all-causes morbidity and mortality; indeed, it is even a predictor of these problems. When properly measured, the assessment of physical fitness can be a highly valuable indicator of health and life expectancy and, therefore, should be performed routinely in the clinical setting. Individually adapted training programs could be prescribed based on fitness assessment results and an adequate knowledge of patient lifestyle and daily physical activity. Such training programs would allow people to develop their maximum physical potential, improve their physical and mental health, and attenuate the negative consequences of aging.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.