ReviewGene therapy2008
Toward 'SMART' stem cells.
Review in Gene therapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Pediatric leukemia: origins, pathogenesis, the role of microenvironment and immunological modulation.Frontiers in immunology · 2026Review
- The spatiotemporal heterogeneity of the biophysical microenvironment during hematopoietic stem cell development: from embryo to adult.Stem cell research & therapy · 2023Review
- Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300.Haematologica · 2023Article
- Emerging roles of extracellular vesicles in normal and malignant hematopoiesis.The Journal of clinical investigation · 2022Review
- Understanding the "SMART" features of hematopoietic stem cells and beyond.Science China. Life sciences · 2021Review
- An urgent need for standardization of stem cells and stem cell-derived products toward clinical applications.Stem cells translational medicine · 2021Article
- Optimizing autologous hematopoietic stem cell transplantation for acute leukemia.Stem cells translational medicine · 2021Review
- Biomechanical cues as master regulators of hematopoietic stem cell fate.Cellular and molecular life sciences : CMLS · 2021Review
- Hematopoietic Stem Cell Niche During Homeostasis, Malignancy, and Bone Marrow Transplantation.Frontiers in cell and developmental biology · 2021Review
- StemCellCKB: An Integrated Stem Cell-Specific Chemogenomics KnowledgeBase for Target Identification and Systems-Pharmacology Research.Journal of chemical information and modeling · 2016Article
- Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow.Leukemia · 2016Article
- Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells.Stem cells and development · 2013Article
- An opposite effect of the CDK inhibitor, p18(INK4c) on embryonic stem cells compared with tumor and adult stem cells.PloS one · 2012Article
- Bid is a positive regulator for donor-derived lymphoid cell regeneration in γ-irradiated recipients.Experimental hematology · 2011Article
- Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging.International journal of hematology · 2011Article
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- Article
- ADAR1 is required for hematopoietic progenitor cell survival via RNA editing.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
Abstract
Stem cell research is at the heart of regenerative medicine, which holds great promise for the treatment of many devastating disorders. However, in addition to hurdles posed by well-publicized ethical issues, this emerging field presents many biological challenges. What is a stem cell? How are embryonic stem cells different from adult stem cells? What are the physiological bases for therapeutically acceptable stem cells? In this editorial review, I will briefly discuss these superficially simple but actually rather complex issues that surround this fascinating cell type. The goal of this special issue on stem cells in Gene Therapy is to review some fundamental and critical aspects of current stem cell research that have translational potential.
Indexed as
Identifiers
18046429What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.