ArticleNucleic acids research2008
GRSDB2 and GRS_UTRdb: databases of quadruplex forming G-rich sequences in pre-mRNAs and mRNAs.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed, 110 citations in OpenAlex.
- Quadrupia provides a comprehensive catalog of G-quadruplexes across genomes from the tree of life.Genome research · 2025Article
- A Dataset Curated for the Assessment of G4s in the LncRNAs Dysregulated in Various Human Cancers.Scientific data · 2025Article
- GAIA: G-quadruplexes in alive creature database.Nucleic acids research · 2023Article
- G4Atlas: a comprehensive transcriptome-wide G-quadruplex database.Nucleic acids research · 2023Article
- QUADRatlas: the RNA G-quadruplex and RG4-binding proteins database.Nucleic acids research · 2023Article
- G-quadruplexes and associated proteins in aging and Alzheimer's disease.Frontiers in aging · 2023Review
- Aptamers targeting amyloidogenic proteins and their emerging role in neurodegenerative diseases.The Journal of biological chemistry · 2022Review
- How bioinformatics resources work with G4 RNAs.Briefings in bioinformatics · 2021Review
- Topology-based classification of tetrads and quadruplex structures.Bioinformatics (Oxford, England) · 2020Article
- Non-duplex G-Quadruplex Structures Emerge as Mediators of Epigenetic Modifications.Trends in genetics : TIG · 2019Review
- A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization.Genome research · 2018Article
- Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome.Nature medicine · 2018Article
- RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF.Genes & development · 2017Article
- Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress.BMC genomics · 2017Article
- RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.Journal of molecular biology · 2017Review
- RNA G-quadruplexes: emerging mechanisms in disease.Nucleic acids research · 2017Article
- Structure, Properties, and Biological Relevance of the DNA and RNA G-Quadruplexes: Overview 50 Years after Their Discovery.Biochemistry. Biokhimiia · 2016Article
- QuadBase2: web server for multiplexed guanine quadruplex mining and visualization.Nucleic acids research · 2016Article
- Directly lighting up RNA G-quadruplexes from test tubes to living human cells.Nucleic acids research · 2015Article
- G4RNA: an RNA G-quadruplex database.Database : the journal of biological databases and curation · 2015Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
G-quadruplex motifs in the RNA play significant roles in key cellular processes and human disease. While sequences capable of forming G-quadruplexes in the pre-mRNA are involved in regulation of polyadenylation and splicing events in mammalian transcripts, the G-quadruplex motifs in the UTRs may help regulate mRNA expression. GRSDB2 is a second-generation database containing information on the composition and distribution of putative Quadruplex-forming G-Rich Sequences (QGRS) mapped in approximately 29 000 eukaryotic pre-mRNA sequences, many of which are alternatively processed. The data stored in the GRSDB2 is based on computational analysis of NCBI Entrez Gene entries with the help of an improved version of the QGRS Mapper program. The database allows complex queries with a wide variety of parameters, including Gene Ontology terms. The data is displayed in a variety of formats with several additional computational capabilities. We have also developed a new database, GRS_UTRdb, containing information on the composition and distribution patterns of putative QGRS in the 5'- and 3'-UTRs of eukaryotic mRNA sequences. The goal of these experiments has been to build freely accessible resources for exploring the role of G-quadruplex structure in regulation of gene expression at post-transcriptional level. The databases can be accessed at the G-Quadruplex Resource Site at: http://bioinformatics.ramapo.edu/GQRS/.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.