ArticlePLoS medicine2007
Clinical trials and medical care: defining the therapeutic misconception.
Article in PLoS medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 175 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
175 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Placebo Rates in Crohn's Disease Randomized Clinical Trials: An Individual Patient Data Meta-Analysis.Gastroenterology · 2025Pooled it
- Participants' understanding of informed consent in clinical trials: A systematic review and updated meta-analysis.PloS one · 2024Pooled it
- Precision cancer medicine and the doctor-patient relationship: a systematic review and narrative synthesis.BMC medical informatics and decision making · 2023Pooled it
- Randomized controlled trials in patients with COVID-19: a systematic review and critical appraisal.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Pooled it
- Pooled it
- Trial
- Therapeutic Misestimation in Patients with Degenerative Ataxia: Lessons from a Randomized Controlled Trial.Movement disorders : official journal of the Movement Disorder Society · 2023Trial
- Deferred consent in emergency obstetric research: findings from qualitative interviews with women and recruiters in theBMJ open · 2022Trial
- Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase caregivers knowledge?BMC medical ethics · 2020Trial
- Ethics of treatment interruption trials in HIV cure research: addressing the conundrum of risk/benefit assessment.Journal of medical ethics · 2018Trial
- Reducing therapeutic misconception: A randomized intervention trial in hypothetical clinical trials.PloS one · 2017Trial
- Trial
- Trial
- Trial
- Community perceptions, trust, and experiences of malaria clinical research and participation in rural Cambodia.Tropical medicine and health · 2026Article
- Social Media Influencer Marketing as a Clinical Trial Recruitment Modality: Tutorial Informed by One Study's Approach.Journal of medical Internet research · 2026Article
- "We're all just trying to do right by our patients": a qualitative study of healthcare and research personnel's moral experiences of engaging with COVID-19 research during the first wave of the pandemic.BMC health services research · 2026Article
- Adults with Intellectual Disability and Consent to Precision Medicine Research: Using Supported Decision-Making to Facilitate First-Person Consent.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2026Article
- Randomized clinical trials and informed consent in pediatric oncology: a Nordic comparative study of parents' experiences.Frontiers in pediatrics · 2026Article
- Identifying Barriers and Motivators to Increase Surgical Clinical Trial Participation for Older Veterans.Journal of the American Geriatrics Society · 2026Article
115 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.