Evidence map›Paper›PMID 18044111›Full record

ReviewClinical interventions in aging2006

Economic considerations in the management of Alzheimer's disease.

Carolyn W Zhu, Mary Sano

Open access · goldAbstract readReview
In one paragraph

Review in Clinical interventions in aging, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. A review of the methods used to estimate the cost of Alzheimer's disease in the United States.American journal of Alzheimer's disease and other dementias · 2011
    Pooled it
  2. Use of services by community-dwelling patients with dementia: a systematic review.American journal of Alzheimer's disease and other dementias · 2011
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. A comprehensive review of discovery and development of drugs discovered from 2020-2022.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Natural Products for Neurodegeneration: Regulating Neurotrophic Signals.Oxidative medicine and cellular longevity · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Astroglia in Alzheimer's Disease.Advances in experimental medicine and biology · 2019
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Carolyn W ZhuGeriatric Research, Education, and Clinical Center (GRECC) and Program of Research on Serious Physical and Mental Illness,Targeted Research Enhancement Program (TREP), Bronx VA Medical Center, Bronx, NY 10468. USA. carolyn.zhu@mssm.edu
Mary Sano
Geriatric Research Education and Clinical Center · USJames J. Peters VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease is a devastating chronic disease that significantly increases healthcare costs and affects the quality of life (QoL) of the afflicted patients and their caregivers. Population aging and other demographic changes may further increase the already staggering costs of this devastating disease. While few pharmacoeconomic studies have used a prospective health economics design to assess resource utilization, most studies showed beneficial treatment effects and suggested potential savings in healthcare costs and reductions in caregiver burden. Various degrees of cost savings have been reported depending on the type of economic model, treatment evaluated, and region used in the studies. Direct comparisons of the results are difficult because different methods have been used in these evaluations. The preference of patients and families for home care for as long as possible suggests that promoting noninstitutional care for these patients should become a priority. Continued home care for patients under pharmacological treatment may reduce caregiver burden, healthcare costs, and ultimately improve patients' and caregivers' QoL.

Indexed as

Health ExpendituresAlzheimer DiseaseCaregiversCholinesterase InhibitorsClinical Trials as TopicHome NursingHumansIncidenceModels, EconometricPrevalenceQuality of LifeSeverity of Illness IndexCholinesterase Inhibitors

Identifiers

PMID18044111
PMCPMC2695165
OpenAlexW1964354767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.