Evidence map›Paper›PMID 18042695›Full record

ReviewJournal of clinical pathology2007

Molecular aspects of HTLV-I infection and adult T-cell leukaemia/lymphoma.

G Taylor

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of clinical pathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Absence of FLT3 mutations in Iranian adult T-cell leukemia/lymphoma patients.Medical journal of the Islamic Republic of Iran · 2018
    Article
  3. Article
  4. Article
  5. Adult T-cell leukaemia/lymphoma.Journal of clinical pathology · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

G TaylorInfectious Diseases Section, Division of Medicine Faculty, St Mary's Campus, Imperial College London, London, UK. g.p.taylor@imperial.ac.uk
Imperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human T-cell lymphotropic virus-I (HTLV-I) is the cause of adult T-cell leukaemia/lymphoma. Various viral proteins, especially, but not exclusively, Tax have been implicated in oncogenesis, mostly through in vitro studies. Tax transactivates a large and apparently ever expanding list of human genes through transcriptional factors. Elucidating not only the pathways but also the timing of action of HTLV proteins is important for understanding the pathogenesis and development of new treatments.

Indexed as

AdultApoptosisCell CycleCell Transformation, NeoplasticCell Transformation, ViralGene Products, taxGenomic InstabilityHTLV-I InfectionsHumansLeukemia-Lymphoma, Adult T-CellTranscription FactorsViral Regulatory and Accessory ProteinsGene Products, taxtax protein, Human T-lymphotrophic virus 1Transcription FactorsViral Regulatory and Accessory Proteins

Identifiers

PMID18042695
PMCPMC2095577
OpenAlexW2058472410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.