Evidence map›Paper›PMID 18042690›Full record

ReviewJournal of clinical pathology2007

Contribution of the Epstein Barr virus to the molecular pathogenesis of Hodgkin lymphoma.

G Kapatai, P Murray

Abstract readReview
In one paragraph

Review in Journal of clinical pathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

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  12. The role of immunohistochemistry in the assessment of classical Hodgkin lymphoma microenvironment.International journal of clinical and experimental pathology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

G KapataiThe Cancer Research UK Institute for Cancer Studies, Medical School, University of Birmingham, Birmingham, UK.
P Murray

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the morphology of the pathognomonic Reed-Sternberg cells of Hodgkin lymphoma (HL) was described over a century ago, it was not until recently that their origin from B lymphocytes was recognised. The demonstration that a proportion of cases of HL harbour the Epstein-Barr virus (EBV) and that its genome is monoclonal in these tumours suggests that the virus contributes to the development of HL in some cases. This review summarises current knowledge of the pathogenesis of HL with particular emphasis on the association with EBV.

Indexed as

Cell Transformation, NeoplasticCell Transformation, ViralEpstein-Barr Virus InfectionsGenes, ViralHerpesvirus 4, HumanHodgkin DiseaseHumansImmunotherapyReed-Sternberg Cells

Identifiers

PMID18042690
PMCPMC2095570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.