ArticleJournal of clinical laboratory analysis2007
A panel of multiple markers associated with chronic systemic inflammation and the risk of atherogenesis is detectable in asthma and chronic obstructive pulmonary disease.
Article in Journal of clinical laboratory analysis, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Asthma and risk of cardiovascular disease or all-cause mortality: a meta-analysis.Annals of Saudi medicinePooled it
- Asthma is associated with atherosclerotic artery changes.PloS one · 2017Trial
- Central hemodynamics in prehypertension: effect of the β-adrenergic antagonist nebivolol.Journal of clinical hypertension (Greenwich, Conn.) · 2013Trial
- Associations of asthma with cardiometabolic diseases and multimorbidity: A cohort study in the UK Biobank.NPJ primary care respiratory medicine · 2025Article
- Association of estimated pulse wave velocity with asthma risk in middle-aged and older adults in China: a national cohort study.BMC public health · 2025Article
- Biological pathways and mechanisms linking COPD and cardiovascular disease.Therapeutic advances in chronic disease · 2025Review
- Blood Eosinophil Count in Asthma Is Associated With Increased Abdominal Aortic Diameter and Increased Vascular Stiffness.Journal of asthma and allergy · 2025Article
- Blood eosinophil count is associated with early atherosclerotic artery changes in asthma.BMC pulmonary medicine · 2024Article
- Investigation of arterial-cardiac-pulmonary interaction.Heart and vessels · 2019Article
- Arterial Stiffness, Distensibility, and Strain in Asthmatic Children.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Occupational exposure levels of bioaerosol components are associated with serum levels of the acute phase protein Serum Amyloid A in greenhouse workers.Environmental health : a global access science source · 2016Article
- Pulmonary Remodeling in Equine Asthma: What Do We Know about Mediators of Inflammation in the Horse?Mediators of inflammation · 2016Review
- Systemic Inflammation in Older Adults With Asthma-COPD Overlap Syndrome.Allergy, asthma & immunology research · 2014Article
- New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease.The American journal of pathology · 2014Review
- Signal relay by CC chemokine receptor 2 (CCR2) and formylpeptide receptor 2 (Fpr2) in the recruitment of monocyte-derived dendritic cells in allergic airway inflammation.The Journal of biological chemistry · 2013Article
- Arterial inflammation in bronchial asthma.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Airway epithelial regulation of allergic sensitization in asthma.Pulmonary pharmacology & therapeutics · 2012Review
- Asthma and proinflammatory conditions: a population-based retrospective matched cohort study.Mayo Clinic proceedings · 2012Article
- Determination of inflammatory biomarkers in patients with COPD: a comparison of different assays.BMC medical research methodology · 2012Article
- Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma and chronic obstructive pulmonary disease (COPD) are both lung diseases involving chronic inflammation of the airway. The injury is reversible in asthma whereas it is mostly irreversible in COPD. Both patients of asthma and COPD are known at risk for cardiovascular disease (CVD) and type 2 diabetes (T2DM), nephropathy, and cancer. We measured multiple risk markers for atherogenesis in 55 patients with asthma and 62 patients with COPD. We wanted to know whether risk markers for atherogenesis corresponding to sequence of events of chronic inflammation were also detectable in the airway inflammatory diseases. Elevation of almost all markers involving inflammation of the endothelial cells in the coronary artery were detectable in asthma and COPD involving the inflammation of the epithelial cell lining of the airway. Both the level and % elevation of all markers were found mostly higher in COPD, the more severe form of the lung disease. We believe that these markers are useful for predicting risk of developing clinical complications such as CVD.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.