Evidence map›Paper›PMID 18040864›Full record

ReviewJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2007

RanBPM, a scaffolding protein in the immune and nervous systems.

L Charles Murrin, Jeffery N Talbot

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 84 citations in OpenAlex.

  1. CD39 and CD161 modulate Th17 responses in Crohn's disease.Journal of immunology (Baltimore, Md. : 1950) · 2014
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  10. Scorpins in the DNA Damage Response.International journal of molecular sciences · 2018
    Review
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  13. TheFrontiers in plant science · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

L Charles MurrinDepartment of Pharmacology and Experimental Neuroscience, 985800 Nebraska Medical Center, Omaha, NE 68198-5800, USA. cmurrin@unmc.edu
Jeffery N Talbot
Nebraska Medical Center · USOhio Northern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We review the literature for Ran Binding Protein in the Microtubule-Organizing Center (RanBPM; RanBP9), a 90-kDa protein that possesses many characteristics of a scaffolding protein, including protein-interaction motifs, a cytoskeletal-binding domain, and multiple canonical docking sites for signaling intermediates. We focus on studies that have examined functional interactions between RanBPM and other proteins. These studies suggest that RanBPM provides a platform for the interaction of a variety of signaling proteins, including cell surface receptors, nuclear receptors, nuclear transcription factors, and cytosolic kinases. These studies indicate that RanBPM acts as a scaffolding protein and is important in regulating cellular function in both the immune system and the nervous system.

Indexed as

Adaptor Proteins, Signal TransducingAmino Acid SequenceAnimalsCytoskeletal ProteinsHumansImmune SystemMolecular Sequence DataNervous SystemNuclear Matrix-Associated ProteinsNuclear Proteinsran GTP-Binding ProteinSignal TransductionAdaptor Proteins, Signal TransducingCytoskeletal ProteinsNuclear Matrix-Associated ProteinsNuclear ProteinsRan binding protein 9ran GTP-Binding Protein

Identifiers

PMID18040864
OpenAlexW2099381742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.