Evidence map›Paper›PMID 18040807›Full record

ReviewJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2006

Endocannabinoids and reactive nitrogen and oxygen species in neuropathologies.

Allyn C Howlett, Somnath Mukhopadhyay, Derek C Norford

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Endocannabinoids in neuroendopsychology: multiphasic control of mitochondrial function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2012
    Review
  3. Article
  4. Article
  5. Endocannabinoids and the heart.Journal of cardiovascular pharmacology · 2009
    Review
  6. Article
  7. Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke.Cardiovascular & hematological agents in medicinal chemistry · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Allyn C HowlettNeuroscience of Drug Abuse Research Program, 208 Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, 700 George Street, Durham, NC 27707, USA. ahowlett@nccu.edu
Somnath Mukhopadhyay
Derek C Norford

Funding

ROLES OF INFLAMMATION AND ANDROGEN METABOLISM IN PROSTATE CANCER DISPARITYP20MD000175 · NIMHD · NORTH CAROLINA CENTRAL UNIVERSITY · PI KIMBRO, KEVIN SEAN · 2002 to 2016
$15.6M
v-Ha-ras Transgene Expression in TgAC MiceS06GM008049 · NIGMS · NORTH CAROLINA CENTRAL UNIVERSITY · PI GRANT, DELORES JUANITA · 1989 to 2009
$5.7M
CANNABINOID RECEPTORS IN NEURONAL CELLS AND BRAINR01DA003690 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOWLETT, ALLYN C · 1985 to 2014
$2.8M
NIDA DRUG ABUSE RESEARCH COLLABORATIONU24DA012385 · NIDA · NORTH CAROLINA CENTRAL UNIVERSITY · PI COLE, GREGORY J · 1998 to 2006
$2.5M
NIDA NIH HHS R01 DA003690NIDA NIH HHS R01-DA03690NIDA NIH HHS U24 DA012385NIDA NIH HHS U24-DA12385NIGMS NIH HHS S06 GM08049NIMHD NIH HHS P20-MD00175PHS HHS K05-00182
6 · The paper itself

Abstract

Neuropathologies that affect our population include ischemic stroke and neurodegenerative diseases of immune origin, including multiple sclerosis. The endocannabinoid system in the brain, including agonists anandamide (arachidonyl ethanolamide) and 2-arachidonoylglycerol, and the CB1 and CB2 cannabinoid receptors, has been implicated in the pathophysiology of these disease states, and can be a target for therapeutic interventions. This review concentrates on cellular signal transduction pathways believed to be involved in the cellular damage.

Indexed as

EndocannabinoidsAnimalsBrainBrain DiseasesCannabinoid Receptor ModulatorsHumansReactive Nitrogen SpeciesReactive Oxygen SpeciesReceptors, CannabinoidSignal TransductionCannabinoid Receptor ModulatorsEndocannabinoidsReactive Nitrogen SpeciesReactive Oxygen SpeciesReceptors, Cannabinoid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.