ArticleVirchows Archiv : an international journal of pathology2008
Analysis of follicular lymphoma by dual-color fluorescence in situ hybridization.
Article in Virchows Archiv : an international journal of pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- A new method for real-time evaluation of pepsin digestion of paraffin-embedded tissue sections, prior to fluorescence in situ hybridisation.Virchows Archiv : an international journal of pathology · 2017Article
- New developments in the pathology of malignant lymphoma: a review of the literature published from January to April 2008.Journal of hematopathology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Follicular lymphoma (FL) is divided into two groups: one with the t(14;18)(q32;q21) and the other without this translocation but with other chromosomal abnormalities including t(3q27) break. The majority of FLs in Western countries have the former chromosomal changes with characteristic clinical features and low histological grades. The goal of this study was to investigate the characteristics of Korean FLs with regard to the underlying molecular defects. Sixty-one cases of FL were evaluated from two centers in Korea by immunostaining for CD10, bcl-2, and bcl-6 proteins. Fluorescence in situ hybridization was performed to detect the t(14;18) and t(3q27) break. Cases with FL grade 3 accounted for 57% of all 61 cases. The t(14;18) was detected in 43.9% of the cases studied, and the frequency was 80, 50, 34.8, and 9.1% from grade 1 through grade 3b. The t(3q27) was detected in 16.1% of cases. Cases without a t(14;18) were mainly histological grade 3 (P < 0.001) and had a tendency to have the t(3q27) and bcl-2 amplification. The incidence of t(14;18)-positive low-grade FL was found to be lower in Korea than in Western countries. The increased frequency of t(14;18)-negative grade 3 FL attributes to the lower incidence of t(14;18) in Korean FL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.