ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2008
NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse.
Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Evidence for the in vivo existence and mobilisation of myeloid angiogenic cells and pericyte-like cells in wound patients after skin grafting.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2023Article
- Ninjurin1 Deletion in NG2-Positive Pericytes Prevents Microvessel Maturation and Delays Wound Healing.JID innovations : skin science from molecules to population health · 2022Article
- Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair.Frontiers in cell and developmental biology · 2021Article
- Article
- Photobiomodulation drives pericyte mobilization towards skin regeneration.Scientific reports · 2020Article
- In vivo monitoring of hair cycle stages via bioluminescence imaging of hair follicle NG2 cells.Scientific reports · 2018Article
- NG2 Proteoglycan-Dependent Contributions of Pericytes and Macrophages to Brain Tumor Vascularization and Progression.Microcirculation (New York, N.Y. : 1994) · 2016Review
- Role of NG2 proteoglycan in macrophage recruitment to brain tumors and sites of CNS demyelination.Trends in cell & molecular biology · 2016Article
- NG2 Proteoglycan Ablation Reduces Foam Cell Formation and Atherogenesis via Decreased Low-Density Lipoprotein Retention by Synthetic Smooth Muscle Cells.Arteriosclerosis, thrombosis, and vascular biology · 2016Article
- Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle.Stem cells international · 2016Article
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- NG2-proteoglycan-dependent contributions of oligodendrocyte progenitors and myeloid cells to myelin damage and repair.Journal of neuroinflammation · 2015Article
- Proteoglycans in Normal and Healing Skin.Advances in wound care · 2015Article
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- Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity.PloS one · 2012Article
- Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord.Journal of neuroinflammation · 2011Article
- Immortalized CNS pericytes are quiescent smooth muscle actin-negative and pluripotent.Microvascular research · 2011Article
- Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury.Brain research · 2011Article
- CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer.Journal of the National Cancer Institute · 2010Article
- Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse.Developmental biology · 2010Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
In early postnatal mouse skin, the NG2 proteoglycan is expressed in the subcutis, the dermis, the outer root sheath of hair follicles, and the basal keratinocyte layer of the epidermis. With further development, NG2 is most prominently expressed by stem cells in the hair follicle bulge region, as also observed in adult human skin. During telogen and anagen phases of the adult hair cycle, NG2 is also found in stem cell populations that reside in dermal papillae and the outer root sheaths of hair follicles. Ablation of NG2 produces alterations in both the epidermis and subcutis layers of neonatal skin. Compared with wild type, the NG2 null epidermis does not achieve its full thickness due to reduced proliferation of basal keratinocytes that serve as the stem cell population in this layer. Thickening of the subcutis is also delayed in NG2 null skin due to deficiencies in the adipocyte population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.