Evidence map›Paper›PMID 18038074›Full record

ArticleBulletin of the World Health Organization2007

Routine offer of antenatal HIV testing ("opt-out" approach) to prevent mother-to-child transmission of HIV in urban Zimbabwe.

Winfreda Chandisarewa, Lynda Stranix-Chibanda, Elizabeth Chirapa, Anna Miller, Micah Simoyi, Agnes Mahomva, Yvonne Maldonado, Avinash K Shetty

Open access · diamondAbstract read
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Article in Bulletin of the World Health Organization, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 6 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 6 syntheses or guidelines pooled it, 179 citations in OpenAlex.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Winfreda ChandisarewaZimbabwe AIDS Prevention Project, University of Zimbabwe, Harare, Zimbabwe.
Lynda Stranix-Chibanda
Elizabeth Chirapa
Anna Miller
Micah Simoyi
Agnes Mahomva
Yvonne Maldonado
Avinash K Shetty
University of Zimbabwe · ZWChitungwiza Municipality · ZWElizabeth Glaser Pediatric AIDS Foundation · USMinistry of Health and Child Welfare · ZWStanford University · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of routine antenatal HIV testing for preventing mother-to-child transmission of HIV (PMTCT) in urban Zimbabwe.

methodsCommunity counsellors were trained in routine HIV testing policy using a specific training module from June 2005 through November 2005. Key outcomes during the first 6 months of routine testing were compared with the prior 6-month "opt-in" period, and clients were interviewed.

findingsOf the 4551 women presenting for antenatal care during the first 6 months of routine HIV testing, 4547 (99.9%) were tested for HIV compared with 3058 (65%) of 4700 women during the last 6 months of the opt-in testing (P < 0.001), with a corresponding increase in the numbers of HIV-infected women identified antenatally (926 compared with 513, P < 0.001). During routine testing, more HIV-infected women collected results compared to the opt-in testing (908 compared with 487, P < 0.001) resulting in a significant increase in deliveries by HIV-infected women (256 compared with 186, P = 0.001); more mother/infant pairs received antiretroviral prophylaxis (n = 256) compared to the opt-in testing (n = 185); and more mother/infant pairs followed up at clinics (105 compared with 49, P = 0.002). Women were satisfied with counselling services and most (89%) stated that offering routine testing is helpful. HIV-infected women reported low levels of spousal abuse and other adverse social consequences.

conclusionRoutine antenatal HIV testing should be implemented at all sites in Zimbabwe to maximize the public health impact of PMTCT.

Indexed as

Urban PopulationAdolescentAdultAnti-HIV AgentsCounselingFemaleHIV InfectionsHumansInfant, NewbornInfectious Disease Transmission, VerticalMental Health ServicesMiddle AgedPregnancyPregnancy Complications, InfectiousPrenatal CareSocial SupportAnti-HIV Agents

Identifiers

PMID18038074
PMCPMC2636259
OpenAlexW2135184715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.