ArticleBulletin of the World Health Organization2007
Magnesium sulfate is not used for pre-eclampsia and eclampsia in Mexico and Thailand as much as it should be.
Article in Bulletin of the World Health Organization, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Prescribing patterns for hypertensive disorders of pregnancy in low- and middle-income countries: a systematic review.BMC pregnancy and childbirth · 2026Pooled it
- Maternal death and obstetric care audits in Nigeria: a systematic review of barriers and enabling factors in the provision of emergency care.Reproductive health · 2016Pooled it
- Magnesium sulphate versus diazepam for eclampsia.The Cochrane database of systematic reviews · 2010Pooled it
- Magnesium sulphate versus phenytoin for eclampsia.The Cochrane database of systematic reviews · 2010Pooled it
- Magnesium sulphate versus lytic cocktail for eclampsia.The Cochrane database of systematic reviews · 2010Pooled it
- Case report: Acute right ventricular dysfunction after surgery in a pregnant patient with congenital heart disease and aortic dissection.Frontiers in cardiovascular medicine · 2023Article
- Factors affecting use of magnesium sulphate for pre-eclampsia or eclampsia: a qualitative evidence synthesis.BJOG : an international journal of obstetrics and gynaecology · 2022Review
- Use of magnesium sulfate before 32 weeks of gestation: a European population-based cohort study.BMJ open · 2017Article
- Transformative Innovations in Reproductive, Maternal, Newborn, and Child Health over the Next 20 Years.PLoS medicine · 2016Review
- Article
- Translating research into policy: lessons learned from eclampsia treatment and malaria control in three southern African countries.Health research policy and systems · 2009Article
- Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia.BMC medical genetics · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn the past ten years effective treatments for pre-eclampsia and eclampsia have been evaluated and identified following large trials and systematic reviews. We investigated the extent of those effective interventions implementation.
methodsDescriptive analysis of data collected as part of a cluster randomized trial. The trial was assigned the International Standardised Randomized Controlled Trial Number ISRCTN 14055385. Hospitals with more than 1000 deliveries per year not directly associated with an academic institution in Mexico City municipal area in Mexico (n = 22) and the north-east region of Thailand (n = 18) were included. All women delivering at the participating hospitals at two time periods in 2000 and 2002 contributed data on practice rates. The use of magnesium sulfate for pre-eclampsia and eclampsia were the outcomes.
findingsEight out of 22 hospitals in Mexico (range 0.8% to 8.5%) and all 18 hospitals in Thailand (range 18.6% to 63.6%) used magnesium sulfate for women with pre-eclampsia. In Mexico, 11 of 22 hospitals used magnesium sulfate for eclampsia (range 9.1% to 60.0%). In Thailand, all 17 hospitals having eclampsia cases used magnesium sulfate (range 25% to 100%).
conclusionDespite compelling evidence, magnesium sulfate use is below desired levels. Clinical practices should be audited and implementation of this effective intervention should be taken up as a priority where universal implementation is not in place.
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