ArticleJournal of medical case reports2007
Brucella bacteremia in patients with acute leukemia: a case series.
Article in Journal of medical case reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Follow-up outcomes of asymptomatic brucellosis: a systematic review and meta-analysis.Emerging microbes & infections · 2023Pooled it
- Febrile neutropenia in an immunocompetent patient with brucellosis: a case report and literature review.Annals of medicine and surgery (2012) · 2025Article
- A case of brucellosis concomitant with HIV infection in China.Infectious diseases of poverty · 2020Article
- Article
- Seroprevalence of Brucellosis in Human Immunodeficiency Virus Infected Patients in Hamadan, Iran.Osong public health and research perspectives · 2017Article
- Brucella abortus Causing Febrile Neutropenia Together with Epididymoorchitis.Indian journal of pediatrics · 2016Article
- A prospective study of brucellosis in children: relative frequency of pancytopenia.Iranian journal of pediatrics · 2014Article
- A prospective study of brucellosis in children: relative frequency of pancytopenia.Mediterranean journal of hematology and infectious diseases · 2013Article
- Brucellosis: a rare cause of febrile neutropenia in acute myeloblastic leukemia.Medical oncology (Northwood, London, England) · 2011Article
- Brucella bacteremia in a recipient of an allogeneic hematopoietic stem cell transplant: a case report.Cases journal · 2009Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBrucellosis may cause serious infections in healthy individuals living in countries that are endemic for the infection. However, reports of brucella infections in immunocompromised hosts are relatively rare. CASE PRESENTATIONS: Reported here are two patients with acute leukemia who developed Brucella melitensis bacteremia during their follow up at the Armed Forces Hospital in Riyadh. The first patient developed B. melitensis bacteremia during the transformation of his myelodysplasia into acute myeloid leukemia. The second patient developed B. melitensis bacteremia while his acute lymphoblastic leukemia was under control. Interestingly, he presented with acute cholecystitis during the brucella sepsis. Both brucella infections were associated with a marked reduction in the hematological parameters in addition to other complications. The bacteremic episodes were successfully treated with netilmicin, doxycycline and ciprofloxacin.
conclusionBrucellosis can cause systemic infections, complicated bacteremia and serious morbidity in patients with acute leukemia living in endemic areas. These infections may occur at the presentation of the leukemia or even when the leukemia is in remission. Nevertheless, the early diagnosis of brucellosis and the administration of appropriate antimicrobial therapy for sufficient duration usually improves the outcome in these immunocompromised patients.
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Registered trials
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