Evidence map›Paper›PMID 18034220›Full record

ReviewHNO2008

[Regenerative medicine in head and neck reconstructive surgery].

F Riedel, U R Goessler, J Stern-Straeter, K Riedel, K Hörmann

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in HNO, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Pathogenesis of chronic wounds].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2008
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

F RiedelUniversitäts-HNO-Klinik Mannheim, Theodor-Kutzer-Ufer, 68135 Mannheim, Deutschland. frank.riedel@hno.ma.uni-heidelberg.de
U R Goessler
J Stern-Straeter
K Riedel
K Hörmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous transplantation is regarded as the gold standard in the treatment of congenital or acquired deformities. However, the availability of autologous tissue for transplantation is often limited. Regenerative medicine aims to activate individuals' own intrinsic regenerative mechanisms and embraces tissue engineering, cell/system biology, gene therapy and stem-cell biology. Most approaches in tissue engineering are based on the expansion of small autologous cell aggregates. Tissue engineering supplemented by isolated and amplified stem cells is another very promising option for producing autologous transplants and getting over the limited availability. The association of stem cell-based tissue engineering and gene therapy allows the creation of regenerative tissue in the optimal ambience of regulatory proteins. This leads to great opportunities in the transplantation of skin, bones or cartilage. This paper presents the current status and the possible benefits, but also the limitations, of regenerative medicine in reconstructive surgery of the head and neck.

Indexed as

Genetic TherapyHumansOtorhinolaryngologic DiseasesOtorhinolaryngologic Surgical ProceduresPlastic Surgery ProceduresRegenerative MedicineStem Cell TransplantationTissue Engineering

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.