Evidence map›Paper›PMID 18032615›Full record

ArticleJournal of clinical microbiology2008

Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D.

Jonas Schmidt-Chanasit, Karoline Bleymehl, Susanne G Schäd, Gerd Gross, Rainer G Ulrich, Hans Wilhelm Doerr

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jonas Schmidt-ChanasitInstitute of Medical Virology, Hospital of the Johann Wolfgang Goethe University, D-60596 Frankfurt am Main, Germany. jonassi@gmx.de
Karoline Bleymehl
Susanne G Schäd
Gerd Gross
Rainer G Ulrich
Hans Wilhelm Doerr
Goethe University Frankfurt · DEUniversity of Rostock · DEFriedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we describe the association of certain varicella-zoster virus (VZV) genotypes with unique glycoprotein E (gE) gene mutations. Within 45 analyzed VZV wild-type strains of genotypes A and D, five novel gE mutations were discovered. A statistically significant (P < 0.0001) association of certain gE mutations with VZV genotype D was found.

Indexed as

Mutation, MissenseAdultAgedAged, 80 and overChickenpoxChildChild, PreschoolDNA, ViralFemaleGenotypeHerpesvirus 3, HumanHerpes ZosterHumansInfantMaleMiddle AgedDNA, Viralglycoprotein E, varicella-zoster virusViral Envelope Proteins

Identifiers

PMID18032615
PMCPMC2224269
OpenAlexW2041978852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.