ReviewJournal of cellular and molecular medicine
Systems biology and cancer stem cells.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Suppressing H19 Modulates Tumorigenicity and Stemness in U251 and U87MG Glioma Cells.Cellular and molecular neurobiology · 2016Article
- Reversible ubiquitination shapes NLRC5 function and modulates NF-κB activation switch.The Journal of cell biology · 2015Article
- Systems biology for molecular life sciences and its impact in biomedicine.Cellular and molecular life sciences : CMLS · 2013Review
- Systems and Network Pharmacology Approaches to Cancer Stem Cells Research and Therapy.Journal of stem cell research & therapy · 2012Article
- A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutations.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Migration rules: tumours are conglomerates of self-metastases.British journal of cancer · 2009Article
- Systems medicine: the future of medical genomics and healthcare.Genome medicine · 2009Article
- Multiway modeling and analysis in stem cell systems biology.BMC systems biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The identification, purification, and characterization of cancer stem cells holds tremendous promise for improving the treatment of cancer. Mounting evidence is demonstrating that only certain tumor cells (i.e. the cancer stem cells) can give rise to tumors when injected and that these purified cell populations generate heterogeneous tumors. While the cell of origin is still not determined definitively, specific molecular markers for populations containing these cancer stem cells have been found for leukemia, brain cancer, and breast cancer, among others. Systems approaches, particularly molecular profiling, have proven to be of great utility for cancer diagnosis and characterization. These approaches also hold significant promise for identifying distinctive properties of the cancer stem cells, and progress is already being made.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.