ArticleDigestive diseases and sciences2008
Diet, lifestyle and gender in gastro-esophageal reflux disease.
Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Association between body mass index at different levels and risk of gastroesophageal reflux disease: a systematic review with dose-response meta-analysis.Frontiers in physiology · 2025Pooled it
- Association between physical activity and risk of gastroesophageal reflux disease: A systematic review and meta-analysis.Journal of sport and health science · 2024Pooled it
- Efficacy and safety of fexuprazan in patients with symptoms and signs of laryngopharyngeal reflux disease: a randomized clinical trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Trial
- Severe reflux oesophagitis caused by repeated vomiting due to glucagon-like peptide-1 receptor agonist.BMJ case reports · 2025Article
- Article
- Tobacco and COPD: presenting the World Health Organization (WHO) Tobacco Knowledge Summary.Respiratory research · 2024Review
- Shift work and risk of incident gastroesophageal reflux disease: the association and mediation.Frontiers in public health · 2023Article
- Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update.Nutrients · 2022Review
- Extra-esophageal symptoms in individuals with and without erosive esophagitis: a case-control study in Albania.BMC gastroenterology · 2021Article
- Dietary and Lifestyle Factors Related to Gastroesophageal Reflux Disease: A Systematic Review.Therapeutics and clinical risk management · 2021Review
- The relationship between reflux symptoms and glycogenic acanthosis lesions of the oesophagus.Przeglad gastroenterologiczny · 2020Article
- Prevalence and risk factors of gastroesophageal reflux disease among Shaqra University students, Saudi Arabia.Journal of family medicine and primary care · 2019Article
- Association between Lifestyle and Gastroesophageal Reflux Disease Questionnaire Scores: A Cross-Sectional Study of 37 442 Chinese Adults.Gastroenterology research and practice · 2019Article
- Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature.Current gastroenterology reports · 2017Review
- Regional Food Causing Symptoms of Gastroesophageal Reflux Disease.Journal of neurogastroenterology and motility · 2017Article
- Foods Inducing Typical Gastroesophageal Reflux Disease Symptoms in Korea.Journal of neurogastroenterology and motility · 2017Article
- Factors associated with complicated erosive esophagitis: A Japanese multicenter, prospective, cross-sectional study.World journal of gastroenterology · 2017Observational
- Dietary carbohydrate intake, insulin resistance and gastro-oesophageal reflux disease: a pilot study in European- and African-American obese women.Alimentary pharmacology & therapeutics · 2016Article
- Review of Clinical Spectrum of Gastroesophageal Reflux Disease in a General Population; A Study from South-East Iran.Middle East journal of digestive diseases · 2016Article
- Dietary habits and gastroesophageal reflux disease in preschool children.Korean journal of pediatrics · 2016Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies indicate that gastro-esophageal reflux disease (GERD) is associated with obesity, smoking, esophagitis, diet, and lifestyle.
aimTo identify risk factors associated with GERD among patients presenting to a tertiary GI clinic in Italy.
methodsPatients with a first diagnosis of GERD based on heartburn and/or regurgitation and/or esophagitis at the endoscopic examination were enrolled. A control group with neither GERD symptoms nor esophagitis was enrolled from the same hospital. Each subject completed a questionnaire including demographic information, lifestyle (e.g., exercise, alcohol, coffee, chocolate, and soda consumption, smoking, having large meals), and frequency of bowel movement. For each participant the body mass index (BMI) was calculated.
resultsFive hundred subjects were enrolled including 300 GERD patients and 200 controls. Females had significantly higher prevalence of GERD than males (66 vs. 48%, P = 0.001, OR = 2.1, 95% CI = 1.5-3.1). There was an inverse relationship between the level of education and presence of GERD (76% of GERD patients has completed only elementary school (OR = 2.1, 95% CI = 1.7-4.9). Obesity (BMI of > or =95th percentile for their age/gender specific) was significantly related to GERD (OR = 1.8, P = 0.01). None of the other variables studied showed significant associations with GERD. Logistic regression analysis showed that BMI > or =95th percentile, gender, and low education level were significant risk factors for GERD.
conclusionsUnderstanding the epidemiology and risk factors for GERD in a region is the first step in designing prevention and treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.