Evidence map›Paper›PMID 18029195›Full record

ArticleJournal of the American Society for Mass Spectrometry2007

A low-noise, wideband preamplifier for a Fourier-transform ion cyclotron resonance mass spectrometer.

Raman Mathur, Ronald W Knepper, Peter B O'Connor

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Fellgett Revisited: On the Nature of Noise in Two-Dimensional Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2024
    Article
  3. Developments in FTICR-MS and Its Potential for Body Fluid Signatures.International journal of molecular sciences · 2015
    Review
  4. Article
  5. Article
  6. Artifacts in Fourier transform mass spectrometry.Rapid communications in mass spectrometry : RCM · 2009
    Article
  7. Article
  8. First signal on the cryogenic Fourier-transform ion cyclotron resonance mass spectrometer.Journal of the American Society for Mass Spectrometry · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raman MathurDepartment of Electrical and Computer Engineering, Boston University, Boston, Massachusetts 2118, USA.
Ronald W Knepper
Peter B O'Connor

Funding

XI INTERNATIONAL SYMPOSIUM ON AMYLOIDOSISP41RR010888 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 1996 to 2011
$18.6M
Defining the IsoAspartomeR01GM078293 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LIN, CHENG · 2007 to 2011
$1.5M
NHLBI PROTEOMICS INITIATIVE-N01HV28178N01HV028178 · HV · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2002 to 2006
–
STRUCTURAL CHARACTERIZATION OF THE APOPROTEIN E RECEPTORR01HL028178 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI INNERARITY, THOMAS L. · 1986 to 1988
–
NCRR NIH HHS P41 RR010888NCRR NIH HHS P41RR10888NHLBI NIH HHS N01 HV028178NIGMS NIH HHS R01 GM078293
6 · The paper itself

Abstract

FTMS performance parameters such as limits of detection, dynamic range, sensitivity, and even mass accuracy and resolution can be greatly improved by enhancing its detection circuit. An extended investigation of significant design considerations for optimal signal-to-noise ratio in an FTMS detection circuit are presented. A low noise amplifier for an FTMS is developed based on the discussed design rules. The amplifier has a gain of approximately 3500 and a bandwidth of 10 kHz to 1 MHz corresponding to m/z range of 100 Da to 10 kDa (at 7 Tesla). The performance of the amplifier was tested on a MALDI-FTMS, and has demonstrated a 25-fold reduction in noise in a mass spectrum of C(60) compared with that of a commercial amplifier.

Indexed as

Amplifiers, ElectronicFourier AnalysisNoiseCyclotronsElectric ImpedanceFullerenesMass SpectrometryFullerenes

Identifiers

PMID18029195
PMCPMC2872042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.