Evidence map›Paper›PMID 18028868›Full record

ArticleArchives of oral biology2008

Sexual dimorphism of murine masticatory muscle function.

David W Daniels, Zuozhen Tian, Elisabeth R Barton

Open access · greenAbstract read
In one paragraph

Article in Archives of oral biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Sexual dimorphisms in skeletal muscle: current concepts and research horizons.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Masticatory muscles of mouse do not undergo atrophy in space.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David W DanielsDepartment of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Zuozhen Tian
Elisabeth R Barton
University of Pennsylvania · US

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
Texas Tech Center for Translational Research and Rural Health - Research Capacity CoreU54MD020892 · NIMHD · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI Lance R. McMahon, Naima Moustaid-Moussa · 2026 to 2026
$10.0M
Modulation of Muscle Regenerationby Growth FactorsR01AR057363 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI BARTON, ELISABETH R · 2010 to 2014
$1.4M
NIAMS NIH HHS R01 AR057363NIAMS NIH HHS U54 AR052646NIAMS NIH HHS U54AR052646NIMHD NIH HHS U54 MD020892
6 · The paper itself

Abstract

objectiveTo determine if gender distinctions of force generating capacity existed in murine masticatory muscles.

designIn order to investigate the effect of sex on force generating capacity in this muscle group, an isolated muscle preparation was developed utilising the murine anterior deep masseter. Age-matched male and female mice were utilized to assess function, muscle fibre type and size in this muscle.

resultsMaximum isometric force production was not different between age-matched male and female mice. However, the rate of force generation and relaxation was slower in female masseter muscles. Assessment of fibre type distribution by immunohistochemistry revealed a three-fold decrease in the proportion of myosin heavy chain 2b positive fibres in female masseters, which correlated with the differences in contraction kinetics.

conclusionsThese results provide evidence that masticatory muscle strength in mice is not affected by sex, but there are significant distinctions in kinetics associated with force production between males and females.

Indexed as

Bite ForceSex CharacteristicsAnimalsBiomechanical PhenomenaFemaleIsometric ContractionMaleMasticatory MusclesMiceMuscle Fibers, Skeletal

Identifiers

PMID18028868
PMCPMC2262833
OpenAlexW1995909089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.