ArticleApplied spectroscopy2007
Raman spectroscopic measurement of relative concentrations in mixtures of oral bacteria.
Article in Applied spectroscopy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Raman signatures ofFrontiers in microbiology · 2026Article
- In Situ Raman Analysis of Biofilm Exopolysaccharides Formed inInternational journal of molecular sciences · 2023Article
- Raman Imaging of PathogenicFrontiers in microbiology · 2021Article
- Identification of different bacterial species in biofilms using confocal Raman microscopy.Journal of biomedical opticsArticle
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Authors and funding
3 authors.
Funding
Abstract
Near-infrared Raman spectroscopy has been used for species identification of pure microbial specimens for more than a decade. More recently, this optical method has been extended to the analysis of specimens containing multiple species. In this report, we demonstrate rapid, reagent-free quantitative analysis of a simplified model of oral plaque containing three oral bacteria species, S. mutans, S. sanguis, and S. gordonii, using near-infrared Raman spectroscopy. Raman spectra were acquired from bacterial mixtures in 200 seconds. A prediction model was calibrated by the partial least squares method and validated by additional samples. On a scale from 0 to 1, relative fractions of each species could be predicted with a root mean square error of 0.07. These results suggest that near-infrared Raman spectroscopy is potentially useful in quantification of microbial mixtures in general and oral plaques in particular.
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Registered trials
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