Trial reportHernia : the journal of hernias and abdominal wall surgery2008
The effect of supplemental 70% oxygen on postoperative nausea and vomiting in patients undergoing inguinal hernia surgery.
Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Perioperative oxygen therapy in patients undergoing surgical procedures: an overview of systematic reviews and meta-analyses.Health technology assessment (Winchester, England) · 2025Pooled it
- Intraoperative respiratory and hemodynamic strategies for reducing nausea, vomiting, and pain after surgery: Systematic review and meta-analysis.Acta anaesthesiologica Scandinavica · 2022Pooled it
- Supplementary oxygen for nonhypoxemic patients: O2 much of a good thing?Critical care (London, England) · 2011Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative nausea and vomiting (PONV) are among the leading side-effects after surgery performed under general anaesthesia. The role of oxygen as an important method for treatment of PONV was studied. The aim of this study was to compare intraoperative 30% oxygen with 70% oxygen for improvement of PONV in patients undergoing inguinal hernia surgery.
methodsIn a clinical double-blind study, patients (n=100) undergoing inguinal hernia surgery were given a standardized halothane anesthetic. After induction, they were randomly assigned to the following two groups: routine oxygen administration with 30% oxygen, balance nitrogen ("30% oxygen group," n=50) and supplemental oxygen administration with 70% oxygen, balance nitrogen ("70% oxygen group," n=50). The overall incidence of nausea and vomiting during the initial postoperative 24 h and correlation between arterial oxygen saturation and incidence of PONV was evaluated.
resultsThere was significant difference in PONV incidence between the two studied groups (14.3% in group treated with 70% oxygen versus 40.0% in group treated with 30% oxygen, P<0.0001). There was a positive correlation between increase in arterial oxygen saturation and decrease in PONV incidence (P<0.0001).
conclusionSupplemental oxygen effectively prevents postoperative nausea and vomiting after inguinal hernia surgery: the higher the arterial oxygen saturation, the less frequent PONV.
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