ArticleAnnals of family medicine
Development and internal validation of the male osteoporosis risk estimation score.
Article in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 54 citations in OpenAlex.
- A comprehensive evaluation of seven osteoporosis screening tools.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Review
- Male osteoporosis: pathophysiology, risk assessment, and evidence-based management.Turkish journal of medical sciences · 2026Review
- Osteoporosis in Men: an Overlooked Patient Population.Current osteoporosis reports · 2025Review
- Osteoporosis in men-East and West: Can the twain meet? A perspective from Asia.Osteoporosis and sarcopenia · 2024Review
- A Machine Learning-Based Preclinical Osteoporosis Screening Tool (POST): Model Development and Validation Study.JMIR aging · 2023Article
- Osteoporosis Screening and Fracture Risk Assessment Tool: Its Scope and Role in General Clinical Practice.Cureus · 2022Review
- Development of the Asia Pacific Consortium on Osteoporosis (APCO) Framework: clinical standards of care for the screening, diagnosis, and management of osteoporosis in the Asia-Pacific region.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Urinary N-telopeptide: The New Diagnostic Test for Osteoporosis.Surgery journal (New York, N.Y.) · 2019Article
- Factors associated with osteoporosis in patients with chronic obstructive pulmonary disease-a nationwide retrospective study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Osteoporosis and Prevalent Fractures among Adult Filipino Men Screened for Bone Mineral Density in a Tertiary Hospital.Endocrinology and metabolism (Seoul, Korea) · 2016Article
- Relationship between pulmonary function and bone mineral density in the Korean National Health and Nutrition Examination Survey.The Korean journal of internal medicine · 2016Article
- Comparison of the Male Osteoporosis Risk Estimation Score (MORES) With FRAX in Identifying Men at Risk for Osteoporosis.Annals of family medicine · 2016Article
- Development and Validation of Osteoporosis Risk-Assessment Model for Korean Men.Yonsei medical journal · 2016Article
- A New Predictive Index for Osteoporosis in Men under 70 Years of Age: An Index to Identify Male Candidates for Osteoporosis Screening by Bone Mineral Density.Journal of osteoporosis · 2014Article
- Association of bone mineral density with airway obstruction and emphysema.Tuberculosis and respiratory diseases · 2012Article
- Recommendations for Diagnosis and Management of Osteoporosis in COPD Men.ISRN rheumatology · 2011Article
- Assessment of determinants for osteoporosis in elderly men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009Article
- Screening Tools for Osteoporosis in India: Where Do We Place Them in Current Clinical Care?Journal of mid-life healthReview
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeWe wanted to develop and validate a clinical prediction rule to identify men at risk for osteoporosis and subsequent hip fracture who might benefit from dual-energy x-ray absorptiometry (DXA).
methodsWe used risk factor data from the National Health and Nutrition Examination Survey III to develop a best fitting multivariable logistic regression model in men aged 50 years and older randomized to either the development (n = 1,497) or validation (n = 1,498) cohorts. The best fitting model was transformed into a simplified scoring algorithm, the Male Osteoporosis Risk Estimation Score (MORES). We validated the MORES, comparing sensitivity, specificity, and area under the receiver operating characteristics (ROC) curve in the 2 cohorts and assessed clinical utility with an analysis of the number needed-to-screen (NNS) to prevent 1 additional hip fracture.
resultsThe MORES included 3 variables-age, weight, and history of chronic obstructive pulmonary disease-and showed excellent predictive validity in the validation cohort. A score of 6 or greater yielded an overall sensitivity of 0.93 (95% CI, 0.85-0.97), a specificity of 0.59 (95% CI, 0.56-0.62), and an area under the ROC curve of 0.832 (95% CI, 0.807-0.858). The overall NNS to prevent 1 additional hip fracture was 279 in a cohort of men representative of the US population.
conclusionsOsteoporosis is a major predictor of hip fractures. Experts believe bisphosphonate treatment in men should yield results similar to that in women and reduce hip fracture rates associated with osteoporosis. In men aged 60 years and older, the MORES is a simple approach to identify men at risk for osteoporosis and refer them for confirmatory DXA scans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.